Some aspects of artificial caries lesion formation of human dental enamel in vitro.

Investigations of artificial carious lesion formation of human dental enamel showed great variability in caries susceptibility. Human specimens were demineralized in acid buffers with Ca and phosphate ions, undersaturated with respect to hydroxyapatite. Under nearly all conditions the results varied from no lesion formations to etching. This may be due to properties of the surface layer such as fluoride content and permeability.