General Medicine, Kamineni Institute of Medical Sciences, Narketpally, Telangana, India.
Radiology, Sree Venkateswara Diagnostics, Kadapa, Andhra Pradesh, India.
BMJ Case Rep. 2022 Mar 7;15(3):e246285. doi: 10.1136/bcr-2021-246285.
SummaryHabitual cough suppression leading to non-tuberculous mycobacteria infections and bronchiectasis has been reported. We present a case of a 55-year-old woman with a chronic history of cough with mild expectoration and frequent lower respiratory tract infections, remitting with antibiotic therapy and other supportive measures. She also reported habitual cough suppression for several years. She was eventually diagnosed with Mycobacterium avium complex (MAC) positive right middle lobe bronchiectasis-Lady Windermere syndrome and obstructive sleep apnoea (OSA), causing disabling symptoms limiting her daily activities. We aim to highlight two key issues-diagnosing MAC infections in a tuberculosis endemic country, and OSA and its long-term clinical implications.
有报道称，习惯性咳嗽抑制可导致非结核分枝杆菌感染和支气管扩张症。我们报告了一例 55 岁女性慢性咳嗽，伴有轻度咳痰和频繁下呼吸道感染，经抗生素治疗和其他支持措施可缓解。她还报告了几年的习惯性咳嗽抑制。最终，她被诊断为鸟分枝杆菌复合群（MAC）阳性右中叶支气管扩张症-温德米尔夫人综合征和阻塞性睡眠呼吸暂停（OSA），导致严重的症状，限制了她的日常活动。我们旨在强调两个关键问题——在结核病流行国家诊断 MAC 感染，以及 OSA 及其长期的临床意义。
