Radiology Department, University Hospital Center of Porto, Porto, Portugal
Breast Unit and Radiology Department, Champalimaud Clinical Center / Champalimaud Foundation, Lisbon, Portugal.
BMJ Case Rep. 2022 Mar 7;15(3):e247900. doi: 10.1136/bcr-2021-247900.
Eccrine porocarcinoma is a rare skin adnexal malignant neoplasm that may arise from a pre-existing benign eccrine poroma or without a predisposing factor. It is a highly invasive neoplasm and has a strong metastatic potential. The most frequently affected organs are the lymph nodes and rarely solid organs such as the liver, lungs and breast. We report a case of a woman with a history of surgically treated eccrine porocarcinoma that a year later presented with multiple lesions in both breasts and axillary lymphadenopathies. After a detailed imaging investigation, the diagnosis of metastatic lesions from porocarcinoma was made. To our knowledge, until the moment, only one case of breast metastasis of eccrine porocarcinoma has been reported in the literature.
大汗腺癌是一种罕见的皮肤附属器恶性肿瘤,可能来源于先前存在的良性大汗腺瘤,也可能无诱发因素。它是一种高度侵袭性的肿瘤,具有很强的转移潜能。最常受累的器官是淋巴结,很少累及肝脏、肺和乳腺等实体器官。我们报告了一例女性患者,曾患有手术治疗的大汗腺癌,一年后出现双侧乳房多个病变和腋窝淋巴结病。经过详细的影像学检查,诊断为大汗腺癌转移病变。据我们所知,目前为止,文献中仅报道过一例大汗腺癌的乳腺转移病例。