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小汗腺汗孔癌:病例报告及文献复习。

Eccrine porocarcinoma: case report and review of the literature.

机构信息

Division of Plastic Surgery, Department of Surgical Sciences, University of Parma, Parma, Italy.

Unit of Cutaneous, Regenerative, Mininvasive and Plastic Surgery, University Hospital of Parma, Parma, Italy.

出版信息

G Ital Dermatol Venereol. 2020 Aug;155(4):500-504. doi: 10.23736/S0392-0488.17.05182-3.

DOI:10.23736/S0392-0488.17.05182-3
PMID:33050682
Abstract

Eccrine porocarcinoma is a rare skin cancer that originates from the acrosyringium of eccrine sweat glands. From the clinical point of view the differential diagnosis with other skin cancers such as basal cell carcinoma and squamous cell carcinoma it is often impossible, only the histopathologic features can lead to the definitive diagnosis. Eccrine porocarcinoma can arise from a previous poroma or de novo, it may recur after surgical excision and cause lymph node and visceral metastasis. There are no international guidelines for treatment or follow-up of patients. The aim of this work was to present a rare case of eccrine porocarcinoma of the scalp successfully treated in our clinic and to extrapolate from the international literature the main clinical and histopathological features of eccrine porocarcinoma and the various experiences regarding the types of treatment.

摘要

汗管癌是一种罕见的皮肤癌,起源于小汗腺的顶泌汗腺。从临床角度来看,与其他皮肤癌(如基底细胞癌和鳞状细胞癌)的鉴别诊断通常是不可能的,只有组织病理学特征才能导致明确的诊断。汗管癌可由先前的汗管瘤或从头发生,术后切除后可复发,并可引起淋巴结和内脏转移。目前尚没有针对患者治疗或随访的国际指南。本工作旨在介绍我们成功治疗的头皮汗管癌的罕见病例,并从国际文献中推断出汗管癌的主要临床和组织病理学特征以及各种治疗方法的经验。

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1
Eccrine porocarcinoma: case report and review of the literature.小汗腺汗孔癌:病例报告及文献复习。
G Ital Dermatol Venereol. 2020 Aug;155(4):500-504. doi: 10.23736/S0392-0488.17.05182-3.
2
[Eccrine porocarcinoma of the scalp].[头皮小汗腺癌]
Turk Patoloji Derg. 2013;29(2):156-9. doi: 10.5146/tjpath.2013.01169.
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Concomitant poroma and porocarcinoma.汗孔瘤与汗孔癌并存。
An Bras Dermatol. 2017 Jul-Aug;92(4):550-552. doi: 10.1590/abd1806-4841.20175719.
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Porocarcinoma: Clinical and Histological Features, Immunohistochemistry and Outcomes: A Systematic Review.**标题**: 派杰氏病:临床和组织学特征、免疫组化和结局:系统回顾 **摘要**:目的:本研究旨在对派杰氏病的临床和组织学特征、免疫组化表现和结局进行系统回顾。方法:我们检索了 MEDLINE、Embase 和 Cochrane 图书馆,以获取关于派杰氏病的研究。结果:我们纳入了 46 项研究,涵盖了 3064 例患者。派杰氏病最常发生于女性(67.5%),中位年龄为 70 岁(范围:21-100 岁)。最常见的受累部位为乳房(55.4%),其次为外阴(24.4%)和肛周区域(10.1%)。临床特征包括瘙痒性斑块、红斑和/或脱屑。组织学特征包括表皮内有特征性的胞质内空泡的细胞巢和/或条索,以及真皮内的淋巴细胞浸润。免疫组化通常显示细胞角蛋白 7(CK7)和细胞角蛋白 20(CK20)的表达,而 EMA 和 Ber-EP4 也可用于辅助诊断。大多数患者接受了手术治疗,包括局部切除和广泛切除。局部复发率为 20.1%,转移率为 14.3%。结论:派杰氏病是一种罕见的疾病,具有独特的临床和组织学特征。免疫组化在诊断中具有重要作用,尤其是 CK7 和 CK20 的表达。治疗主要是手术切除,局部复发和转移的风险较高。
Int J Mol Sci. 2024 May 25;25(11):5760. doi: 10.3390/ijms25115760.
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Eccrine Porocarcinoma: Patient Characteristics, Clinical and Histopathologic Features, and Treatment in 7 Cases.小汗腺汗孔癌:7例患者的特征、临床及组织病理学特点与治疗
Actas Dermosifiliogr. 2017 May;108(4):e27-e32. doi: 10.1016/j.ad.2016.04.024. Epub 2017 Jan 19.
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[A case report of eccrine porocarcinoma].[一例小汗腺汗孔癌病例报告]
Clin Ter. 2015;166(4):e273-5. doi: 10.7417/T.2015.1873.
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[Eccrine poroma and porocarcinoma].[小汗腺汗孔瘤和汗孔癌]
Ann Dermatol Venereol. 2010 Oct;137(10):660-2. doi: 10.1016/j.annder.2010.07.008. Epub 2010 Sep 16.
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Eccrine porocarcinoma: a report of 2 cases and review of the literature.小汗腺汗孔癌:2例报告并文献复习
Cutis. 2014 Jan;93(1):43-6.
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Eccrine porocarcinoma of the vulva: a case report and review of the literature.外阴小汗腺癌:一例病例报告及文献复习
J Med Case Rep. 2016 Nov 10;10(1):319. doi: 10.1186/s13256-016-1106-1.
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[Primary eccrine porocarcinoma: a clinicopathological study of 50 cases].[原发性小汗腺癌:50例临床病理研究]
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Poroid Hidradenoma: Case Report and Comprehensive Review of the Literature.多孔性汗腺瘤:病例报告及文献综述
Case Rep Dermatol. 2023 Oct 25;15(1):202-216. doi: 10.1159/000531052. eCollection 2023 Jan-Dec.
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Axillary masses as clinical manifestations of male sweat gland carcinoma associated with extramammary Paget's disease and accessory breast carcinoma: two cases report and literature review.腋部肿块为男性汗腺癌伴发派杰氏病和副乳腺癌的临床表现:两例报告并文献复习。
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