Sims M, Artal R, Quach H, Wu P Y
J Perinat Med. 1986;14(2):123-6. doi: 10.1515/jpme.1986.14.2.123.
Jitteriness is a common problem affecting neonates. Although the cause can sometimes be determined by history or conventional laboratory evaluations, nevertheless, in many instances the cause of the jitteriness is unknown. To determine if either intracranial hemorrhage (ICH) or elevated catecholamines are responsible for jitteriness in neonates, we studied 34 healthy term neonates with normal hematocrits, serum glucose, Ca, Mg, Na, K and P. Thirteen of the infants had jitteriness as their only clinical problem. There were no differences in Apgar scores, birthweight, or gestational age in the two groups. Norepinephrine levels were significantly elevated in the jittery group as compared to the control group: 1276 +/- 574 vs. 914 +/- 338, p less than 0.05. Epinephrine levels were not different in the two groups. Intracranial hemorrhage was not found in any of the patients. Jittery neonates have increased sympathetic activity. What influence the increased levels have on other metabolic and hormonal systems is yet to be determined.
易激惹是影响新生儿的常见问题。虽然有时可通过病史或常规实验室检查确定病因，但在许多情况下，易激惹的病因尚不清楚。为了确定颅内出血（ICH）或儿茶酚胺升高是否是新生儿易激惹的原因，我们研究了34名血细胞比容、血清葡萄糖、钙、镁、钠、钾和磷正常的足月健康新生儿。其中13名婴儿仅有易激惹这一临床问题。两组在阿氏评分、出生体重或胎龄方面无差异。与对照组相比，易激惹组的去甲肾上腺素水平显著升高：1276±574 vs. 914±338，p<0.05。两组肾上腺素水平无差异。所有患者均未发现颅内出血。易激惹的新生儿交感神经活动增强。这些升高的水平对其他代谢和激素系统有何影响尚待确定。
