Ren Baixiang, Yu Yaxin, Poopal Rama-Krishnan, Qiao Linlin, Ren Baichuan, Ren Zongming
Institute of Environment and Ecology, Shandong Normal University, 250358 Jinan, China.
Environ Sci Technol. 2022 Apr 5;56(7):4262-4271. doi: 10.1021/acs.est.1c07732. Epub 2022 Mar 8.
We developed an infrared (IR)-based real-time online monitoring device (US Patent No: US 10,571,448 B2) to quantify heart electrocardiogram (ECG) signals to assess the water quality based on physiological changes in fish. The device is compact, allowing us to monitor cardiac function for an extended period (from 7 to 30 days depending on the rechargeable battery capacity) without function injury and disturbance of swimming activity. The electrode samples and the biopotential amplifier and microcontroller process the cardiac-electrical signals. An infrared transceiver transmits denoised electrocardiac signals to complete the signal transmission. The infrared receiver array and biomedical acquisition signal processing system send signals to the computer. The software in the computer processes the data in real time. We quantified ECG indexes (P-wave, Q-wave, R-wave, S-wave, T-wave, PR-interval, QRS-complex, and QT-interval) of carp precisely and incessantly under the different experimental setup (CuSO and deltamethrin). The ECG cue responses were chemical-specific based on CuSO and deltamethrin exposures. This study provides an additional technology for noninvasive water quality surveillance.
我们开发了一种基于红外线(IR)的实时在线监测设备(美国专利号:US 10,571,448 B2),用于量化心脏心电图(ECG)信号,以便根据鱼类的生理变化评估水质。该设备体积小巧,使我们能够长时间监测心脏功能(根据可充电电池容量,从7天到30天不等),而不会对其功能造成损伤,也不会干扰其游泳活动。电极样本以及生物电位放大器和微控制器对心脏电信号进行处理。一个红外收发器传输去噪后的心脏电信号以完成信号传输。红外接收器阵列和生物医学采集信号处理系统将信号发送到计算机。计算机中的软件实时处理数据。我们在不同的实验设置(硫酸铜和溴氰菊酯)下,精确且持续地量化了鲤鱼的心电图指标(P波、Q波、R波、S波、T波、PR间期)。基于硫酸铜和溴氰菊酯暴露,心电图提示反应具有化学特异性。本研究为非侵入性水质监测提供了一项额外技术。