Blanco M T, Hurtado C, Peinado J M
Microbios. 1986;46(186):59-64.
The production of microcin 15, a low molecular weight antibiotic, resistant to proteases and antagonized by methionine, was measured in batch and continuous cultures of E. coli LP 136. The highest yield per cell was obtained in conditions (anaerobiosis, low glucose concentration, low growth rate) similar to those found in the intestinal tract. It is postulated that microcin production may be an important factor in growth competition between enterobacteria in the intestinal tract.
在大肠杆菌LP 136的分批培养和连续培养中，对微菌素15（一种低分子量抗生素，对蛋白酶有抗性且受蛋氨酸拮抗）的产量进行了测定。在类似于肠道中发现的条件（厌氧、低葡萄糖浓度、低生长速率）下，获得了每个细胞的最高产量。据推测，微菌素的产生可能是肠道中肠杆菌之间生长竞争的一个重要因素。
