Öztürk Kerem, Öztürk Arin, Turhal Göksel
Department of Otorhinolaryngology, Ege University Faculty of Medicine, İzmir, Turkey.
Turk Arch Otorhinolaryngol. 2021 Dec;59(4):282-288. doi: 10.4274/tao.2021.2021-8-13. Epub 2022 Feb 22.
Complete en bloc supraglottic tumor excision with transoral laser microsurgery (TLM) can be achieved with good postoperative outcomes. We report surgical feasibility and the postsurgical outcomes of en bloc resection of supraglottic laryngeal squamous cell carcinomas (LSCC) with TLM.
Seventeen patients who underwent TLM for supraglottic laryngeal cancer were included in the study. Demographic and pathological data, clinic and follow-up outcomes of the patients were reviewed and analyzed.
Type 1 TLM was performed in three patients, type 2a in one patient, type 3b in 12 patients, and type 4b in one patient. Negative surgical margins were achieved in all of the cases. Re-excision or any adjuvant treatment for positive resection margins was not required in any of the cases. Eight patients received adjuvant radiotherapy due to lymph node metastasis. Mean follow-up time was 33.8±15.7 months (range: 10-65 months). None of the patients had recurrence or distant metastasis.
The transoral approach with the use of CO laser and microscopy offers complete tumor excision for treating supraglottic LSCC. The three-dimensional structure of the supraglottis can be achieved with adequate exposure. En bloc resection is possible with safe margins.
经口激光显微手术(TLM)可实现声门上肿瘤整块切除,术后效果良好。我们报告了采用TLM整块切除声门喉鳞状细胞癌(LSCC)的手术可行性及术后结果。
本研究纳入了17例行TLM治疗声门喉癌的患者。回顾并分析了患者的人口统计学和病理数据、临床及随访结果。
3例患者行1型TLM,1例患者行2a型,12例患者行3b型,1例患者行4b型。所有病例均实现手术切缘阴性。所有病例均无需因切缘阳性而再次切除或进行任何辅助治疗。8例患者因淋巴结转移接受辅助放疗。平均随访时间为33.8±15.7个月(范围:10 - 65个月)。所有患者均无复发或远处转移。
使用CO激光和显微镜的经口入路可为治疗声门LSCC提供完整的肿瘤切除。通过充分暴露可实现声门上区的三维结构。整块切除可行且切缘安全。