Tan Xinyue, Wang Huadong
Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Songhu Road 2005, Shanghai, 200438, P. R. China.
Chem Soc Rev. 2022 Apr 4;51(7):2583-2600. doi: 10.1039/d2cs00044j.
Borenium ions are strong Lewis acids because of the positive charge on boron. While their high reactivity had long restricted their role in organic synthesis to stoichiometric reagents, in the past ten years the introduction of suitable supporting ligands, such as N-heterocyclic carbenes, has enabled them to function as competent catalysts for various organic transformations involving the activation of strong covalent bonds, such as H-H, Si-H, B-H, C-H and C-C bonds. This review provides an overview of the recent advances in borenium-catalysed reactions with emphasis on catalyst synthesis, methodology development and mechanistic insight.
硼鎓离子因其硼原子上的正电荷而具有很强的路易斯酸性。虽然它们的高反应活性长期以来将其在有机合成中的作用限制为化学计量试剂，但在过去十年中，引入合适的支持配体，如氮杂环卡宾，使它们能够作为各种有机转化的有效催化剂，这些转化涉及强共价键的活化，如H-H、Si-H、B-H、C-H和C-C键。本综述概述了硼鎓催化反应的最新进展，重点介绍了催化剂合成、方法开发和机理研究。
