Lovera Sergio O, Bagsdasarian Alex L, Guo Juchen, Nelson Hosea M, Lavallo Vincent
Departments of Chemistry, University of California Riverside, Riverside, CA 92521, USA.
Department of Chemistry and Chemical Engineering, Pasadena, CA 91125, USA.
Chem Commun (Camb). 2022 Mar 24;58(25):4060-4062. doi: 10.1039/d2cc00173j.
C-H functionalization of undecahalogenated carborane anions, [HCBX] (X = Cl, Br, I), is performed with CsCO in acetonitrile. We show that the requisite Cl, Br and I carborane dianions can all be efficiently accessed with CsCO. The utilization of CsCO eliminates the complications associated with competing E2 elimination reactions providing an efficient, more functional group tolerant, and broader scope than previously reported. The ensuing functionalized cages provide potential synthons for constructing advanced materials and other molecular architectures for various applications.
在乙腈中，用碳酸铯对十一卤代碳硼烷阴离子[HCBX]（X = Cl、Br、I）进行碳-氢官能团化反应。我们表明，碳酸铯能够有效地制备所需的氯、溴和碘碳硼烷二阴离子。使用碳酸铯消除了与竞争性E2消除反应相关的复杂性，提供了一种比先前报道更高效、更具官能团耐受性且适用范围更广的方法。由此产生的官能团化笼状化合物为构建用于各种应用的先进材料和其他分子结构提供了潜在的合成子。
