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儿童消化道重复畸形——15 年经验总结。

Alimentary tract duplications in children - a 15 years' experience.

机构信息

Discipline of Physiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania;

出版信息

Rom J Morphol Embryol. 2021 Jul-Sep;62(3):751-756. doi: 10.47162/RJME.62.3.12.

Abstract

Duplications of the alimentary tract are a diverse and complex spectrum of congenital malformations and can be found anywhere along the digestive tract. The management depends on multiple factors, such as age, location, size, macroscopic aspect, and the associated anomalies. This study reflects a 15-year single surgical team experience. We reviewed medical records of 35 consecutive patients presenting alimentary tract duplications, evaluated and managed between 2004 and 2019. The anatomical distribution included: oral structures (two cases), esophageal (three cases), gastric (three patients), jejunoileal (seven cases), ileocecal (12 cases), colonic (six cases), anorectal (one case), and one case of complex tubular duplication of the terminal ileum and entire colon with two anal openings at the perineum. Four patients had antenatal diagnosis, initially asymptomatic, were followed, after birth, with repeated ultrasound examinations for a medium period of 3.8 months. All cases were managed with open surgery. Excision of the lesion with preservation of the gut integrity could be performed in 28 of the cases, while in six cases, enterectomy followed by digestive anastomosis was required. In one complex caudal duplication syndrome, the duplicated tubular colon was left in place. The postoperative complications were gastroesophageal reflux disease (GERD) (two cases), Claude Bernard-Horner syndrome (one case), wound infection (one case), and in one case, massive tongue edema. Clinical findings may be misleading, imaging studies may be uncertain, therefore the surgeon remains to complete de picture with intraoperative findings. In complex duplication cases, a multidisciplinary approach is imperative for the best results.

摘要

消化道重复畸形是一组多样化和复杂的先天性畸形,可发生于消化道的任何部位。其处理取决于多个因素,如年龄、位置、大小、大体外观和相关畸形等。本研究反映了一个 15 年的单一外科团队经验。我们回顾了 2004 年至 2019 年间连续 35 例消化道重复畸形患者的医疗记录,对其进行了评估和管理。解剖分布包括:口腔结构(2 例)、食管(3 例)、胃(3 例)、空肠回肠(7 例)、回盲部(12 例)、结肠(6 例)、直肠肛门(1 例)和 1 例复杂的末端回肠和整个结肠管状重复畸形,会阴处有两个肛门开口。4 例有产前诊断,最初无症状,在出生后进行了多次超声检查,随访时间为 3.8 个月。所有病例均采用开放性手术治疗。28 例可通过保留肠道完整性切除病变,6 例需进行肠切除术和消化道吻合术。在 1 例复杂的尾部重复畸形综合征中,保留了重复的管状结肠。术后并发症包括胃食管反流病(GERD)(2 例)、Claude Bernard-Horner 综合征(1 例)、伤口感染(1 例)和 1 例舌部巨大水肿。临床表现可能具有误导性,影像学检查可能存在不确定性,因此外科医生仍需根据术中发现来完成诊断。在复杂的重复畸形病例中,多学科方法是取得最佳结果的必要条件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b60/9019608/2c89a25528e8/RJME-62-3-751-fig1.jpg

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