蛙皮素和胃泌素释放肽对大鼠胃抑制性多肽和胰岛素释放的影响。
Effect of bombesin and gastrin-releasing peptide on the release of gastric inhibitory polypeptide and insulin in rats.
作者信息
Greeley G H, Spannagel A, Trowbridge J, Thompson J C
出版信息
Proc Soc Exp Biol Med. 1986 Sep;182(4):540-2. doi: 10.3181/00379727-182-42377.
PMID:3526356
Abstract
The objective of this study was to determine whether bombesin- or gastrin-releasing peptide-induced release of insulin occurs before or after the release of gastric inhibitory polypeptide (GIP) in rats. The present results demonstrate that GIP release occurs before insulin release and suggest that bombesin-like peptides and GIP interact to stimulate insulin secretion.
摘要
本研究的目的是确定在大鼠中，蛙皮素或胃泌素释放肽诱导的胰岛素释放是在胃抑制性多肽（GIP）释放之前还是之后发生。目前的结果表明，GIP释放在胰岛素释放之前发生，提示类蛙皮素肽和GIP相互作用以刺激胰岛素分泌。
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