[LASEREO内镜系统在早期胃癌中的临床应用]
[Clinical application of LASEREO endoscopic system in early gastric cancer].
作者信息
Lin Y, Zou D D, Zheng H Y, Wu Y L, Lin T, Yang Tuo
机构信息
Department of Gastroenterology, Fuding Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuding 355200, China.
Department of Anus-Intestines, Fuding Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuding 355200, China.
出版信息
Zhonghua Nei Ke Za Zhi. 2022 Mar 1;61(3):310-316. doi: 10.3760/cma.j.cn112138-20210328-00246.
To evaluate the clinical application of LASEREO endoscopic system in early gastric cancer (EGC). A total of 68 patients diagnosed with EGC were retrospectively analyzed between August 2017 to December 2020 in Fuding Hospital Affiliated to Fujian University of Traditional Chinese Medicine. There were 50 males and 18 females finally enrolled with a median age of 64 years. EGCs were analyzed from subjective and objective aspect, as well as from magnification and non-magnification status. Six endoscopists evaluated the visibility of the EGC (RSC) and calculated the color difference (ΔEC) between EGC and the surrounding mucosa in white light imaging (WLI), blue light imaging-bright (BLI-Bri) and linked color imaging (LCI) modes. In the case of magnification (×80), the visibility of the microstructures and microvessels (RSV) was analyzed and the color difference (ΔEV) between microvessels and non-vessels areas were calculated in WLI, BLI and LCI modes. The visibility was evaluated using visibility ranking scale(RS) and the color difference (ΔE) was calculated using Lab* color space. In WLI, BLI-Bri, and LCI modes, the mean (±SD) RSC were 2.56±0.68, 2.63±0.59 and 3.17±0.50, and the mean(±SD) ΔEC were 15.71±5.58, 12.04±3.73, and 22.84±8.46, respectively, which in LCI were higher than those in WLI and BLI-Bri modes (0.001).Regarding the data evaluated by senior endoscopists, the RSC was higher in BLI-Bri than that in WLI mode (2.98±0.58 vs. 2.79±0.73, 0.001), but as to those evaluated by junior endoscopists, there were no significant differences between the WLI and BLI-Bri modes(2.29±0.72 vs. 2.23±0.72,P =0.218).In magnifying endoscopy with WLI, BLI, and LCI modes, the mean(±SD) RSV were 2.95±0.28, 3.46±0.40, and 3.38±0.33, and the mean (±SD) ΔEV were 21.68±7.52, 44.29±10.94, and 45.38±14.29, respectively.The RSV and ΔEV in LCI and BLI were higher than that in WLI mode (0.001). LCI improves the visibility of EGC by increasing ΔEC, especially in junior endoscopists. Both BLI and LCI improve the visibility of microstructures and microvessels under magnification.
评估LASEREO内镜系统在早期胃癌（EGC）中的临床应用。回顾性分析2017年8月至2020年12月在福建中医药大学附属福鼎医院诊断为EGC的68例患者。最终纳入50例男性和18例女性，中位年龄64岁。从主观和客观方面以及放大和非放大状态分析EGC。六位内镜医师评估EGC的可视性（RSC），并计算白光成像（WLI）、蓝光成像-明亮模式（BLI-Bri）和链接彩色成像（LCI）模式下EGC与周围黏膜之间的色差（ΔEC）。在放大（×80）情况下，分析微观结构和微血管的可视性（RSV），并计算WLI、BLI和LCI模式下微血管与非血管区域之间的色差（ΔEV）。使用可视性等级量表（RS）评估可视性，使用Lab*颜色空间计算色差（ΔE）。在WLI、BLI-Bri和LCI模式下，平均（±标准差）RSC分别为2.56±0.68、2.63±0.59和3.17±0.50，平均（±标准差）ΔEC分别为15.71±5.58、12.04±3.73和22.84±8.46，LCI模式下的值高于WLI和BLI-Bri模式（P =0.001）。关于高级内镜医师评估的数据，BLI-Bri模式下的RSC高于WLI模式（2.98±0.58对2.79±0.73，P =0.001），但对于初级内镜医师评估的数据，WLI和BLI-Bri模式之间无显著差异（2.29±0.72对2.23±0.72，P =0.218）。在WLI、BLI和LCI模式的放大内镜检查中，平均（±标准差）RSV分别为2.95±0.28、3.46±0.40和3.38±0.33，平均（±标准差）ΔEV分别为21.68±7.52、44.29±10.94和45.38±14.29。LCI和BLI模式下的RSV和ΔEV高于WLI模式（P =0.001）。LCI通过增加ΔEC提高EGC的可视性，尤其是在初级内镜医师中。BLI和LCI均提高放大状态下微观结构和微血管的可视性。
Zotero 插件