Department of Rehabilitation Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Department of Women's Health Nursing & Midwifery, Tohoku University Graduate School of Medicine, Miyagi, Japan.
Drug Discov Ther. 2022;16(1):37-42. doi: 10.5582/ddt.2022.01004.
Persistence of urinary incontinence (UI) after robot-assisted radical prostatectomy (RARP) is a bothersome problem because of its negative effect on the patient's quality of life (QOL). This study aimed to evaluate the effect of transperineal ultrasound (TPUS)-guided pelvic floor muscle training (PFMT) on prolonged UI after RARP. Thirty men with stress UI persisting for > 1 year after RARP underwent biofeedback PFMT using TPUS once every 2-3 weeks for 3 months. The frequency and duration of sustaining pelvic floor muscle (PFM) contractions were assessed using ultrasound imaging. The severity of UI and UI-related QOL were evaluated using a 24-hour pad test and the incontinence quality of life (I-QOL) questionnaire. Twenty-four men (mean age, 72.2 years) completed the TPUS-guided PFMT. The mean duration from RARP to PFMT was 1,228.9 days. The mean cumulative session and the total duration of TPUS-guided PFMT were 4.6 times and 73.3 days, respectively. Compared with the data before TPUS-guided PFMT, the frequency of PFM contractions and duration of sustaining contraction significantly improved after TPUS-guided PFMT (p < 0.05). Additionally, the total amount of urinary leakage after TPUS-guided PFMT was reduced significantly (248.6 ± 280.6 g vs. 397.0 ± 427.0 g, p = 0.024). The I-QOL score was significantly increased after TPUS-guided PFMT (72.1 ± 16.8 vs. 61.0 ± 19.0, p < 0.001). TPUS-guided PFMT may be effective in improving prolonged UI occurring > 1 year after RARP.
经尿道前列腺切除术(RARP)后持续性尿失禁(UI)是一个令人烦恼的问题,因为它会对患者的生活质量(QOL)产生负面影响。本研究旨在评估经会阴超声(TPUS)引导的盆底肌训练(PFMT)对 RARP 后持续性 UI 的影响。30 名经 RARP 治疗后持续 1 年以上的压力性 UI 男性患者接受了生物反馈 PFMT,每 2-3 周使用 TPUS 治疗一次,共 3 个月。使用超声成像评估盆底肌(PFM)收缩的频率和持续时间。使用 24 小时垫试验和尿失禁生活质量(I-QOL)问卷评估 UI 的严重程度和与 UI 相关的 QOL。24 名男性(平均年龄 72.2 岁)完成了 TPUS 引导的 PFMT。从 RARP 到 PFMT 的平均时间为 1228.9 天。TPUS 引导的 PFMT 的平均累积疗程和总疗程分别为 4.6 次和 73.3 天。与 TPUS 引导的 PFMT 前相比,PFM 收缩的频率和持续收缩的时间在 TPUS 引导的 PFMT 后明显改善(p < 0.05)。此外,TPUS 引导的 PFMT 后总的漏尿量明显减少(248.6 ± 280.6 g 比 397.0 ± 427.0 g,p = 0.024)。TPUS 引导的 PFMT 后 I-QOL 评分明显升高(72.1 ± 16.8 比 61.0 ± 19.0,p < 0.001)。TPUS 引导的 PFMT 可能对改善 RARP 后 1 年以上发生的持续性 UI 有效。