PhD Student N.N. Burdenko National Medical Research Center for Neurosurgery, Ministry of Health of the Russian Federation, 16, 4 Tverskaya-Yamskaya St., Moscow, 125047, Russia.
Professor, Corresponding Member of the Russian Academy of Sciences, Head of 10 Neurosurgery Department; Deputy Director for Science N.N. Burdenko National Medical Research Center for Neurosurgery, Ministry of Health of the Russian Federation, 16, 4 Tverskaya-Yamskaya St., Moscow, 125047, Russia.
Sovrem Tekhnologii Med. 2021;13(5):83-94. doi: 10.17691/stm2021.13.5.10. Epub 2021 Oct 29.
Intramedullary hemangioblastomas (HAB) refer to very rare highly vascularized vascular spinal cord tumors associated with various neurological disorders. Effective HAB therapy to a greater extent depends on diagnostic accuracy and the absence of intra- and postoperative complications. The present study is a review of publications concerned with modern diagnostic and therapeutic techniques to control spinal HAB. The authors showed that perfusion computed tomography, computed tomographic angiography, and magnetic resonance angiography can be reasonably used for diagnosis and differentiation in a number of HAB due to their high vascularization. Preoperative embolization significantly reducing intraoperative bleeding risks is highly efficient. Some authors recommend this procedure in case of large lesions and high risks of intraoperative bleeding. The review also considered intraoperative imaging of a tumor and its feeding vessels using indocyanine green providing inspectability over the total tumor resection and clear imaging of tumor vascular architecture. The advantages and restrictions of the mentioned procedures were described.
脊髓内血管母细胞瘤(HAB)是指与多种神经功能障碍相关的非常罕见的高度血管化的脊髓血管肿瘤。HAB 的有效治疗在更大程度上取决于诊断的准确性和无术中及术后并发症。本研究综述了与控制脊髓 HAB 的现代诊断和治疗技术相关的出版物。作者表明,由于其高度血管化,灌注计算机断层扫描、计算机断层血管造影和磁共振血管造影可合理用于诊断和鉴别诊断多种 HAB。术前栓塞术可显著降低术中出血风险,效率极高。一些作者建议对大病灶和术中出血风险高的患者进行该手术。本综述还考虑了使用吲哚菁绿对肿瘤及其供养血管进行术中成像,可在全肿瘤切除时进行检查,并可清晰显示肿瘤血管结构。还描述了所述手术的优点和局限性。