Bakunowicz-Łazarczyk Alina, Urban Beata, Krętowska Małgorzata
Department of Paediatric Ophthalmology and Strabismus, Medical University of Bialystok, Waszyngtona 17, Bialystok 15-274, Poland.
Faculty of Computer Science, Bialystok University of Technology, Wiejska 45A, Białystok 15-351, Poland.
J Ophthalmol. 2022 Feb 28;2022:4068026. doi: 10.1155/2022/4068026. eCollection 2022.
To evaluate the efficacy of laser peripheral iridotomy (LPI) in preventing deterioration in eyes with ocular hypertension (OHT) and concave configuration of the iris.
This was a retrospective study, which was carried out within a period of 3-5 years. Twenty-four patients with OHT and concave irises were treated with LPI and followed up periodically. IOP, central corneal thickness (CCT), anterior chamber depth (ACD), scleral spur angle (SSA), global neuroretinal rim (NRR) thickness, and global retinal nerve fiber layer (RNFL) were examined before and after LPI.
The average age of the 24 patients was 14.21 ± 1.41 (13-17.5) years on admission. The initial IOP of the 48 eyes was 23.21 ± 1.56 mmHg in RE and 22.96 ± 2.1 mmHg in LE before LPI. All 48 eyes had concave irises in both eyes. All eyes treated with LPI have shown iris flattening, which has persisted during follow-up (mean 1.54 ± 0.9 years). At the last follow-up visit, the average IOP was 17.58 ± 2.63 (14-21) mmHg in RE and 17.58 ± 2.86 (14-21) mmHg in LE, which was statistically lower than that of the baseline ( < 0.001). There were significant changes in SSA in both eyes and global RNFL in RE after LPI.
In the current study, LPI resulted in an IOP-lowering effect and iris flattening in adolescent eyes with a concave configuration of the peripheral iris.
评估激光周边虹膜切开术（LPI）对眼压升高（OHT）且虹膜呈凹面形态的眼睛预防病情恶化的疗效。
这是一项回顾性研究，在3至5年的时间内进行。对24例眼压升高且虹膜呈凹面形态的患者进行了LPI治疗，并定期随访。在LPI治疗前后检查眼压（IOP）、中央角膜厚度（CCT）、前房深度（ACD）、巩膜突角（SSA）、整体神经视网膜边缘（NRR）厚度和整体视网膜神经纤维层（RNFL）。
24例患者入院时的平均年龄为14.21±1.41（13 - 17.5）岁。在LPI治疗前，48只眼睛的右眼初始眼压为23.21±1.56 mmHg，左眼为22.96±2.1 mmHg。所有48只眼睛的双眼虹膜均为凹面形态。所有接受LPI治疗的眼睛均出现虹膜变平，且在随访期间持续存在（平均1.54±0.9年）。在最后一次随访时，右眼平均眼压为17.58±2.63（14 - 21）mmHg，左眼为17.58±2.86（14 - 21）mmHg，统计学上低于基线眼压（<0.001）。LPI治疗后，双眼的SSA以及右眼的整体RNFL均有显著变化。
在本研究中，LPI对周边虹膜呈凹面形态的青少年眼睛具有降低眼压和使虹膜变平的作用。
