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新冠病毒疫苗接种后获得性甲型血友病:一例报告及文献复习

Acquired Hemophilia A Post-COVID-19 Vaccination: A Case Report and Review.

作者信息

Al Hennawi Hussam, Al Masri Mohammad K, Bakir Mohamad, Albarazi Mohieddin, Jazaeri Feras, Almasri Talal N, Shoura Sami J, Barakeh Abdul Rahman R, Taftafa Abdulrahman, Khan Muhammad K, Zaleski Henry I

机构信息

College of Medicine, Alfaisal University College of Medicine, Riyadh, SAU.

Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.

出版信息

Cureus. 2022 Feb 4;14(2):e21909. doi: 10.7759/cureus.21909. eCollection 2022 Feb.

Abstract

Acquired hemophilia A (AHA) is an inhibitory coagulopathy that represents a rare variant of hemorrhagic syndromes. We present a case of idiopathic AHA in a 75-year-old male patient with a cutaneous hematoma that could be attributed to a recent COVID-19 vaccination. The aim of this report is to raise awareness of a possible association between AHA and COVID-19 vaccination and to review similar reported cases and management plans to prevent the development of possible morbidity and debilitating complications. This case illustrates an exceptionally rare side effect of the COVID-19 vaccination. The advantages of obtaining the COVID-19 vaccine outweigh the risks.

摘要

获得性血友病A(AHA)是一种抑制性凝血病,是出血综合征的一种罕见变体。我们报告一例75岁男性特发性AHA病例,其皮肤血肿可能归因于近期的新冠病毒疫苗接种。本报告的目的是提高对AHA与新冠病毒疫苗接种之间可能关联的认识,并回顾类似的报告病例及管理计划,以预防可能的发病和使人衰弱的并发症。该病例说明了新冠病毒疫苗接种一种极其罕见的副作用。接种新冠病毒疫苗的益处大于风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e369/8898568/3fda1469f975/cureus-0014-00000021909-i01.jpg

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