一名接触过新冠病毒的患者发生获得性甲型血友病病例。
A Case of Acquired Hemophilia A in a Patient with Exposure to COVID-19.
作者信息
Guerra Jorge D, Gowarty Jasmine, Buess Jordan, Mason James, Halka Kathleen
机构信息
Department of Internal Medicine, Baylor Scott & White Medical Center, Texas A&M University College of Medicine, Temple, TX, USA.
Department of Hematology and Medical Oncology, Baylor Scott & White Medical Center, Texas A&M University College of Medicine, Temple, TX, USA.
出版信息
Case Rep Hematol. 2022 Mar 22;2022:9494249. doi: 10.1155/2022/9494249. eCollection 2022.
Abstract
Acquired Hemophilia A (AHA) is a very rare autoimmune condition involving immune-mediated depletion of Factor VIII, resulting in spontaneous hemorrhage. Failure to recognize AHA as a possible etiology of hemorrhage can result in delayed diagnosis and treatment. The COVID-19 pandemic has given rise to several hematologic conditions and complications, with a rare manifestation being Acquired Hemophilia A (AHA). An interesting case of AHA following SARS-CoV-2 infection is described, along with the treatment approach and a brief review of several cases describing AHA in association with COVID-19.
摘要
获得性血友病A（AHA）是一种非常罕见的自身免疫性疾病，涉及免疫介导的凝血因子VIII耗竭，导致自发性出血。未能认识到AHA是出血的可能病因可导致诊断和治疗延迟。COVID-19大流行引发了几种血液学疾病和并发症，获得性血友病A（AHA）是一种罕见表现。本文描述了1例新型冠状病毒肺炎（SARS-CoV-2）感染后发生AHA的有趣病例，以及治疗方法，并简要回顾了几例描述AHA与COVID-19相关的病例。
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