艾滋病相关淋巴瘤：进展与新挑战
HIV-Associated Lymphomas: Progress and New Challenges.
作者信息
Pongas Georgios N, Ramos Juan C
机构信息
Department of Medicine, Division of Hematology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
出版信息
J Clin Med. 2022 Mar 7;11(5):1447. doi: 10.3390/jcm11051447.
Abstract
The association of human immunodeficiency virus (HIV) and aggressive lymphomas was first reported in 1982. Before the development of effective HIV antiviral therapy, the incidence and the mortality of these lymphomas was high, with patients frequently succumbing to the disease. More lately, the combination of cART with chemoimmunotherapy significantly improved the survival outcome of the HIV-lymphomas. In this review, we discuss on describing the incidence of HIV-associated lymphomas, their clinical features, and the latest advances in the management of the various lymphoma subtypes.
摘要
人类免疫缺陷病毒（HIV）与侵袭性淋巴瘤的关联首次报道于1982年。在有效的HIV抗病毒治疗出现之前，这些淋巴瘤的发病率和死亡率都很高，患者常常死于该疾病。最近，高效抗逆转录病毒治疗（cART）与化疗免疫疗法的联合显著改善了HIV相关淋巴瘤的生存结局。在本综述中，我们将讨论HIV相关淋巴瘤的发病率、临床特征以及各种淋巴瘤亚型治疗的最新进展。
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