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利用片上超宽带雷达设备进行心血管系统的动态微波成象。

Dynamic Microwave Imaging of the Cardiovascular System Using Ultra-Wideband Radar-on-Chip Devices.

出版信息

IEEE Trans Biomed Eng. 2022 Sep;69(9):2935-2946. doi: 10.1109/TBME.2022.3158251. Epub 2022 Aug 19.

Abstract

OBJECTIVE

Microwave imaging has been investigated for medical applications such as stroke and breast imaging. Current systems typically rely on bench-top equipment to scan at a variety of antenna positions. For dynamic imaging of moving structures, such as the cardiovascular system, much higher imaging speeds are required than what has thus far been reported. Recent innovations in radar-on-chip technology allow for simultaneous high speed data collection at multiple antenna positions at a fraction of the cost of conventional microwave equipment, in a small and potentially portable system. The objective of the current work is to provide proof of concept of dynamic microwave imaging in the body, using radar-on-chip technology.

METHODS

Arrays of body-coupled antennas were used with nine simultaneously operated coherent ultra-wideband radar chips. Data were collected from the chest and thigh of a volunteer, with the objective of imaging the femoral artery and beating heart. In addition, data were collected from a phantom to validate system performance. Video data were constructed using beamforming.

RESULTS

The location of the femoral artery could successfully be resolved, and a distinct arterial pulse wave was discernable. Cardiac activity was imaged at locations corresponding to the heart, but image quality was insufficient to identify individual anatomical structures. Static and differential imaging of the femur bone proved unsuccessful.

CONCLUSION

Using radar chip technology and an imaging approach, cardiovascular activity was detected in the body, demonstrating first steps towards biomedical dynamic microwave imaging. The current portable and modular system design was found unsuitable for static in-body imaging.

SIGNIFICANCE

This first proof of concept demonstrates that radar-on-chip could enable cardiovascular imaging in a low-cost, small and portable system. Such a system could make medical imaging more accessible, particularly in ambulatory or long-term monitoring settings.

摘要

目的

微波成像是医学应用领域的一个研究方向,例如中风和乳腺成像。当前的系统通常依赖于台式设备,以在各种天线位置进行扫描。对于移动结构的动态成像,例如心血管系统,需要比迄今为止报告的更高的成像速度。雷达芯片技术的最新创新使得以传统微波设备的一小部分成本,在一个小型且具有潜在便携性的系统中,以多个天线位置同时进行高速数据采集成为可能。当前工作的目的是使用雷达芯片技术为体内心血管微波成像提供概念验证。

方法

使用与九个同时运行的相干超宽带雷达芯片耦合的体耦合天线阵列。从志愿者的胸部和大腿采集数据,目的是对股动脉和跳动的心脏进行成像。此外,还从一个体模中采集数据以验证系统性能。使用波束形成技术构建视频数据。

结果

成功地定位了股动脉的位置,并可以辨别明显的动脉脉搏波。在与心脏相对应的位置对心脏活动进行了成像,但图像质量不足以识别单个解剖结构。对股骨的静态和差分成像均不成功。

结论

使用雷达芯片技术和成像方法,在体内检测到心血管活动,朝着生物医学动态微波成像迈出了第一步。当前的便携式和模块化系统设计不适合静态体内成像。

意义

这一概念验证首次表明,雷达芯片可在低成本、小型且便携的系统中实现心血管成像。这样的系统可以使医疗成像更易获得,特别是在移动或长期监测环境中。

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