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超宽带探测的微波血管造影术:初步研究

Microwave Angiography by Ultra-Wideband Sounding: A Preliminary Investigation.

作者信息

Chamaani Somayyeh, Sachs Jürgen, Prokhorova Alexandra, Smeenk Carsten, Wegner Tim Erich, Helbig Marko

机构信息

Time Domain Electromagnetics Laboratory, Faculty of Electrical Engineering, K. N. Toosi University of Technology, Tehran 16317, Iran.

Electronic Measurements and Signal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany.

出版信息

Diagnostics (Basel). 2023 Sep 14;13(18):2950. doi: 10.3390/diagnostics13182950.

Abstract

Angiography is a very informative method for physicians such as cardiologists, neurologists and neuroscientists. The current modalities experience some shortages, e.g., ultrasound is very operator dependent. The computerized tomography (CT) and magnetic resonance (MR) angiography are very expensive and near infrared spectroscopy cannot capture the deep arteries. Microwave technology has the potential to address some of these issues while compromising between operator dependency, cost, speed, penetration depth and resolution. This paper studies the feasibility of microwave signals for monitoring of arteries. To this aim, a homogenous phantom mimicking body tissue is built. Four elastic tubes simulate arteries and a mechanical system creates pulsations in these arteries. A multiple input multiple output (MIMO) array of ultra-wideband (UWB) transmitters and receivers illuminates the phantom and captures the reflected signals over the desired observation time period. Since we are only interested in the imaging of dynamic parts, i.e., arteries, the static clutters can be suppressed easily by background subtraction method. To obtain a fast image of arteries, which are pulsating with the heartbeat rate, we calculate the Fourier transform of each channel of the MIMO system over the observation time and apply delay and sum (DAS) beamforming method on the heartbeat rate aligned spectral component. The results show that the lateral and longitudinal images and motion mode (M-mode) time series of different points of phantom have the potential to be used for diagnosis.

摘要

血管造影术对于心脏病专家、神经科医生和神经科学家等医生来说是一种非常有用的方法。当前的技术存在一些不足,例如,超声非常依赖操作人员。计算机断层扫描(CT)和磁共振(MR)血管造影术非常昂贵,而近红外光谱无法捕捉深部动脉。微波技术有潜力解决其中一些问题,同时在操作人员依赖性、成本、速度、穿透深度和分辨率之间进行权衡。本文研究了微波信号用于监测动脉的可行性。为此,构建了一个模拟人体组织的均匀体模。四根弹性管模拟动脉,一个机械系统在这些动脉中产生脉动。一个超宽带(UWB)发射机和接收机的多输入多输出(MIMO)阵列照射体模,并在所需的观察时间段内捕捉反射信号。由于我们只对动态部分(即动脉)的成像感兴趣,因此可以通过背景减法轻松抑制静态杂波。为了获得随心跳速率脉动的动脉的快速图像,我们在观察时间内计算MIMO系统每个通道的傅里叶变换,并对与心跳速率对齐的频谱分量应用延迟求和(DAS)波束形成方法。结果表明,体模不同点的横向和纵向图像以及运动模式(M模式)时间序列有用于诊断的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07d3/10528261/95e68eb68159/diagnostics-13-02950-g001.jpg

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