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一种用于在 MRI 中计算靠近医疗植入物的射频场增强的超快计算的微扰方法。

A perturbation approach for ultrafast calculation of RF field enhancements near medical implants in MRI.

机构信息

Computational Imaging Group for MRI diagnostics and therapy, Centre for Image Sciences UMC Utrecht, Utrecht, Utrecht, 3584 CX, The Netherlands.

Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Brabant, 5612 AZ, The Netherlands.

出版信息

Sci Rep. 2022 Mar 10;12(1):4224. doi: 10.1038/s41598-022-08004-7.

Abstract

Patients with medical implants often are deprived of magnetic resonance imaging examination because of safety risks. One specific risk is the enhancement of the radiofrequency fields around the medical implant potentially resulting in significant tissue heating and damage. The assessment of this enhancement is a computationally demanding task, with simulations taking hours or days to converge. Conventionally the source of the radiofrequency fields, patient anatomy, and the medical implant are simulated concurrently. To alleviate the computational burden, we reformulate a fast simulation method that views the medical implant as a small perturbation of the simulation domain without the medical implant and calculates the radiofrequency fields associated with this perturbation. Previously, this method required an extensive offline stage where the result is intractable for large simulation domains. Currently, this offline stage is no longer required and the method is completely online. The proposed method results in comparable radiofrequency fields but is orders of magnitude faster compared to standard simulation technique; the finite-difference time-domain, the finite-sums, and the finite element methods. This acceleration could enable patient-specific and potentially online radiofrequency safety assessment.

摘要

患有医疗植入物的患者通常会因为安全风险而无法接受磁共振成像检查。一个特定的风险是医疗植入物周围的射频场增强,可能导致明显的组织加热和损伤。这种增强的评估是一项计算要求很高的任务,模拟需要数小时或数天才能收敛。传统上,射频场的源、患者解剖结构和医疗植入物是同时模拟的。为了减轻计算负担,我们重新制定了一种快速模拟方法,该方法将医疗植入物视为模拟域中没有医疗植入物的小扰动,并计算与该扰动相关的射频场。以前,这种方法需要一个广泛的离线阶段,其结果对于大型模拟域来说是难以处理的。目前,这个离线阶段已经不再需要,该方法完全是在线的。与标准模拟技术(有限差分时域法、有限和法和有限元法)相比,该方法得到的射频场相当,但速度要快几个数量级。这种加速可以实现患者特定的、潜在的在线射频安全评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faaa/8913743/3b3a8a2534de/41598_2022_8004_Fig1_HTML.jpg

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