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Sacubitril/valsartan-A new weapon for fighting the hypertension paradox.

作者信息

Ohishi Mitsuru

机构信息

Department of Cardiovascular Medicine and Hypertension, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

出版信息

Hypertens Res. 2022 May;45(5):915-916. doi: 10.1038/s41440-022-00872-w. Epub 2022 Mar 10.

DOI:10.1038/s41440-022-00872-w
PMID:35273352
Abstract
摘要

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[Clinical case: early connection of valsartan/sacubitril in the treatment of hypertension].[临床病例：缬沙坦/沙库巴曲早期联用治疗高血压]
Kardiologiia. 2022 May 31;62(5):72-74. doi: 10.18087/cardio.2022.5.n1977.
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Impact of Sacubitril/Valsartan Versus Ramipril on Total Heart Failure Events in the PARADISE-MI Trial.沙库巴曲缬沙坦与雷米普利对PARADISE-MI试验中总体心力衰竭事件的影响。
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The ESC Guidelines on heart failure, sacubitril-valsartan in resistant hypertension, and new therapeutic targets in myocardial hypertrophy.欧洲心脏病学会关于心力衰竭、沙库巴曲缬沙坦用于难治性高血压以及心肌肥厚新治疗靶点的指南。
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[Sacubitril-valsartan should also be the first choice to be evaluated in the elderly patient with heart failure with reduced ejection fraction].沙库巴曲缬沙坦也应作为射血分数降低的老年心力衰竭患者评估的首选药物。
Rev Esp Geriatr Gerontol. 2021 Mar-Apr;56(2):67-68. doi: 10.1016/j.regg.2020.12.006. Epub 2021 Jan 30.
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[Update on the clinical application of valsartan/sacubitril in patients with heart failure].[缬沙坦/沙库巴曲在心力衰竭患者中的临床应用进展]
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Sacubitril-valsartan as a treatment for apparent resistant hypertension in patients with heart failure and preserved ejection fraction.沙库巴曲缬沙坦治疗射血分数保留的心力衰竭伴明显抗高血压治疗失败患者。
Eur Heart J. 2021 Sep 21;42(36):3741-3752. doi: 10.1093/eurheartj/ehab499.

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J Clin Hypertens (Greenwich). 2025 Jan;27(1):e14938. doi: 10.1111/jch.14938. Epub 2024 Dec 4.
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Expert Opinion on the Role of Sacubitril/Valsartan in the Management of Hypertension in India.沙库巴曲缬沙坦在印度高血压管理中作用的专家意见
Cardiol Ther. 2024 Dec;13(4):663-677. doi: 10.1007/s40119-024-00390-5. Epub 2024 Nov 6.
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本文引用的文献

1
Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension.老年高血压患者强化血压控制试验。
N Engl J Med. 2021 Sep 30;385(14):1268-1279. doi: 10.1056/NEJMoa2111437. Epub 2021 Aug 30.
2
Japanese National Plan for Promotion of Measures Against Cerebrovascular and Cardiovascular Disease.日本促进脑血管和心血管疾病防治措施国家计划
Circulation. 2021 May 18;143(20):1929-1931. doi: 10.1161/CIRCULATIONAHA.120.052737. Epub 2021 May 17.
3
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).
Amide-to-Triazole Switch in Somatostatin-14-Based Radioligands: Impact on Receptor Affinity and In Vivo Stability.
基于生长抑素-14的放射性配体中酰胺到三唑的转变：对受体亲和力和体内稳定性的影响。
Pharmaceutics. 2024 Mar 13;16(3):392. doi: 10.3390/pharmaceutics16030392.
4
Comparative analysis of sacubitril/valsartan and losartan potassium in the treatment of hypertension: efficacy, adverse reactions, and observations.沙库巴曲缬沙坦与氯沙坦钾治疗高血压的对比分析：疗效、不良反应及观察
Am J Transl Res. 2023 Sep 15;15(9):5715-5722. eCollection 2023.
5
A gene variant protects against Alzheimer's disease.一种基因变体可预防阿尔茨海默病。
Aging Brain. 2023 Jan 6;3:100063. doi: 10.1016/j.nbas.2022.100063. eCollection 2023.
日本高血压学会高血压管理指南（JSH 2019）。
Hypertens Res. 2019 Sep;42(9):1235-1481. doi: 10.1038/s41440-019-0284-9.
4
Analysis of antihypertensive treatment using real-world Japanese data-the retrospective study of antihypertensives for lowering blood pressure (REAL) study.使用真实世界日本数据的降压治疗分析——降压药物的回顾性研究（REAL 研究）。
Hypertens Res. 2019 Jul;42(7):1057-1067. doi: 10.1038/s41440-019-0238-2. Epub 2019 Mar 6.
5
Impact of diastolic blood pressure threshold for the young population: the Japan Arteriosclerosis Longitudinal Study (JALS).
J Hypertens. 2019 Mar;37(3):652-653. doi: 10.1097/HJH.0000000000002025.
6
Shattuck Lecture. The hypertension paradox--more uncontrolled disease despite improved therapy.沙塔克讲座。高血压悖论——尽管治疗有所改善，但仍有更多疾病未得到控制。
N Engl J Med. 2009 Aug 27;361(9):878-87. doi: 10.1056/NEJMsa0903829.