Liu Jiabin, Wang Chen, Li Qing, Duan Xianggong, Zhu Xiaolian, Wang Jiahong, Du Xiangying, Lu Jie, Li Kuncheng
Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, China.
Front Neurol. 2022 Feb 22;13:616964. doi: 10.3389/fneur.2022.616964. eCollection 2022.
To validate the feasibility of free-breathing, non-gated, high-pitch heart-to-brain computed tomography arteriography (CTA) in acute ischemic stroke and the capability of non-gated heart-to-brain CTA in showing cardiac anatomy.
The study protocol was approved by the institutional medical ethics review board. Free-breathing, non-gated, high-pitch heart-to-brain CTA was performed on patients with acute ischemic stroke referred for multimodal CT using a third-generation dual-source CT. Patients scheduled for ECG-triggered heart-to-brain CTA served as controls. Quantitative and/or qualitative image quality of the four cardiac chambers, left atrial appendage, interventricular and interatrial septa, carotid arteries, and coronary arteries were evaluated and compared between the two groups.
Free-breathing, non-gated, high-pitch heart-to-brain CTA was performed on 30 patients with acute ischemic stroke, whereas the control group included 31 cases. There is no significant difference in the image quality of CTAs between the two groups at cardiac chambers and carotid arteries. The image quality of coronary arteries also showed no significant difference between the two groups. The mean dose length products of CTA in the two groups were 129.1 ± 30.5 mGy cm and 121.6 ± 30.3 mGy cm, respectively. Cardiac abnormality can be shown in patients with acute ischemic stroke.
It is feasible to use free-breathing, non-gated, high-pitch heart-to-brain CTA with dual-source CT in acute ischemic stroke for cardiac etiology screening.
验证自由呼吸、非门控、高螺距心脏至脑CT血管造影（CTA）在急性缺血性卒中中的可行性以及非门控心脏至脑CTA显示心脏解剖结构的能力。
本研究方案经机构医学伦理审查委员会批准。使用第三代双源CT对因多模态CT检查而转诊的急性缺血性卒中患者进行自由呼吸、非门控、高螺距心脏至脑CTA检查。将计划进行心电图触发心脏至脑CTA检查的患者作为对照组。对两组患者的四个心腔、左心耳、室间隔和房间隔、颈动脉及冠状动脉的定量和/或定性图像质量进行评估并比较。
对30例急性缺血性卒中患者进行了自由呼吸、非门控、高螺距心脏至脑CTA检查，而对照组有31例。两组在心腔和颈动脉CTA图像质量方面无显著差异。两组冠状动脉的图像质量也无显著差异。两组CTA的平均剂量长度乘积分别为129.1±30.5 mGy·cm和121.6±30.3 mGy·cm。急性缺血性卒中患者可显示心脏异常。
在急性缺血性卒中中使用双源CT进行自由呼吸、非门控、高螺距心脏至脑CTA检查以筛查心脏病因是可行的。
