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经典玉米突变体的力量:推动我们对植物的基本认识。

The power of classic maize mutants: Driving forward our fundamental understanding of plants.

机构信息

School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.

Department of Plant and Microbial Biology, University of California, Berkeley, California, USA.

出版信息

Plant Cell. 2022 Jul 4;34(7):2505-2517. doi: 10.1093/plcell/koac081.

Abstract

Since Mendel, maize has been a powerhouse of fundamental genetics research. From testing the Mendelian laws of inheritance, to the first genetic and cytogenetic maps, to the use of whole-genome sequencing data for crop improvement, maize is at the forefront of genetics advances. Underpinning much of this revolutionary work are the classic morphological mutants; the "freaks" that stood out in the field to even the untrained eye. Here we review some of these classic developmental mutants and their importance in the history of genetics, as well as their key role in our fundamental understanding of plant development.

摘要

自孟德尔以来,玉米一直是基础遗传学研究的强大力量。从检验孟德尔遗传定律,到第一张遗传和细胞遗传学图谱,再到利用全基因组测序数据进行作物改良,玉米一直处于遗传学进展的前沿。支撑这项革命性工作的是经典的形态突变体;即使是未经训练的人也能一眼看出这些“畸形”在田间的与众不同。在这里,我们回顾了其中一些经典的发育突变体及其在遗传学史上的重要性,以及它们在我们对植物发育的基本理解中的关键作用。

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