Goerz G, Schulte-Beerbühl R, Roder K, Schoppe W D, Münchhoff C, Jungblut R M
Dtsch Med Wochenschr. 1986 Aug 15;111(33):1230-3. doi: 10.1055/s-2008-1068611.
Data on 378 patients with histologically proven malignant melanoma were analysed. Metastases were demonstrated within a few months to maximally 11 years postoperatively in 41 patients by clinical or biochemical examinations, computed tomography, ultrasound or radiology. At the time of the first postoperative staging examination metastases were found by clinical examination in five, by computed tomography in a further two patients. Later follow-up examinations discovered metastases by clinical examination in 32 patients, by chest X-ray in two. It is concluded that postoperative staging does not require elaborate routinely performed tests. Specific studies, admittedly undertaken only after the occurrence of symptoms, should be aimed at determining metastases and their extent so that indications for operation can be established if isolated organ metastases have been demonstrated.
对378例经组织学证实的恶性黑色素瘤患者的数据进行了分析。41例患者在术后数月至最长11年内通过临床或生化检查、计算机断层扫描、超声或放射学检查发现有转移。在首次术后分期检查时,通过临床检查发现5例有转移,另外2例通过计算机断层扫描发现有转移。后来的随访检查通过临床检查发现32例有转移,通过胸部X线检查发现2例有转移。结论是术后分期不需要进行复杂的常规检查。诚然,只有在出现症状后才进行的特定研究,应旨在确定转移情况及其范围,以便在已证实存在孤立器官转移时能够确定手术指征。