Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Department of Pathology, The Ohio State University, Wexner Medical Center, Columbus, OH, USA.
Ann Diagn Pathol. 2022 Jun;58:151932. doi: 10.1016/j.anndiagpath.2022.151932. Epub 2022 Mar 4.
Calyceal diverticula (CD) are relatively uncommon urologic conditions that generally follow an asymptomatic course and rarely require medical intervention. CD are thought to have a congenital origin due to abnormalities during the process of ureteral bud formation. Clinically and radiologically, they can mimic multiple neoplastic and non-neoplastic renal processes, with potentially relevant differences in the management of these patients. Symptoms are usually associated with the presence of stones, obstruction to the drainage of the diverticulum, large size, or secondary infection. In chronic cases, surgery might become necessary, creating an opportunity to examine the histopathological characteristics of this condition. Although these are benign in the majority of patients, some rare instances of malignancy arising from the CD have been reported. In this series, we addressed the clinical, radiological, and histopathological findings of CD.
肾盏憩室(CD)是一种相对少见的泌尿系统疾病,通常呈无症状经过,很少需要医学干预。CD 被认为具有先天性起源,是由于输尿管芽形成过程中的异常所致。在临床上和影像学上,它们可以模拟多种肿瘤性和非肿瘤性的肾脏病变,这些患者的处理可能存在潜在的差异。症状通常与结石的存在、憩室引流受阻、憩室较大或继发感染有关。在慢性病例中,可能需要手术,这为检查这种疾病的组织病理学特征提供了机会。尽管在大多数患者中这些是良性的,但也有一些罕见的 CD 恶变的报道。在本系列中,我们探讨了 CD 的临床、影像学和组织病理学特征。