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明智选择加拿大:加拿大生育和男科协会列出的生育医学领域中医生和患者应质疑的首要项目清单。

Choosing Wisely Canada: Canadian fertility and andrology society's list of top items physicians and patients should question in fertility medicine.

机构信息

Department of Obstetrics and Gynaecology, University of Toronto, 123 Edward St, Toronto, ON, M5G 1E2, Canada.

Mount Sinai Fertility, Sinai Health System, 700-250 Dundas Street West, Toronto, ON, M5T 2Z5, Canada.

出版信息

Arch Gynecol Obstet. 2022 Jul;306(1):267-275. doi: 10.1007/s00404-022-06453-z. Epub 2022 Mar 12.

Abstract

PURPOSE

To create a Choosing Wisely Canada list of the top 5 diagnostic and therapeutic interventions that should be questioned in Reproductive Endocrinology and Infertility in Canada.

METHODS

The Canadian Fertility and Andrology Society (CFAS) National Working Group developed an initial list of recommendations of diagnostic and therapeutic interventions that are commonly used, but are not supported by evidence, and could expose patients to unnecessary harm. These were chosen based on their prevalence, cost, potential for harm, and quality of supporting evidence. A modified Delphi consensus was used over 5 rounds to generate ideas, review supporting evidence, assess clinical relevance, estimate recommendation impact and narrow the recommendations list to 5 items.

RESULTS

Fifty unique ideas were first proposed by the working group, and after 5 rounds including a survey of Canadian Fertility and Andrology Society (CFAS) members, the final list of recommendations was created, including topics related to unnecessary investigations and interventions for patients with infertility and recurrent pregnancy loss, and those undergoing IVF. In this article, we describe not only the Delphi process used to determine the list, but also provide a summary of the evidence behind each of the final recommendations.

CONCLUSIONS

The list of five recommendations highlights opportunities to initiate conversations between clinicians and patients about the risks, benefits, harms and costs of unnecessary fertility treatments and procedures in a Canadian context.

摘要

目的

在加拿大生殖内分泌学和不孕症领域,创建一份加拿大明智选择的前 5 项诊断和治疗干预措施清单,这些干预措施应受到质疑。

方法

加拿大生育与男科协会(CFAS)国家工作组制定了一份初步建议清单,其中包括一些常见但缺乏证据支持的诊断和治疗干预措施,这些措施可能会给患者带来不必要的伤害。这些建议是基于其普遍性、成本、潜在危害和支持证据的质量来选择的。经过 5 轮修改后的德尔菲共识,用于生成想法、审查支持证据、评估临床相关性、估计建议影响并将建议清单缩小至 5 项。

结果

工作组首先提出了 50 个独特的想法,经过 5 轮包括对加拿大生育与男科协会(CFAS)成员的调查,最终确定了建议清单,其中包括与不孕和反复妊娠丢失以及接受 IVF 的患者不必要的检查和干预相关的主题。在本文中,我们不仅描述了用于确定清单的德尔菲过程,还提供了每个最终建议背后证据的摘要。

结论

这 5 项建议清单突出了在加拿大背景下,临床医生和患者之间就不必要的生育治疗和程序的风险、益处、危害和成本进行对话的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/290b/8917376/cad74d73f78b/404_2022_6453_Fig1_HTML.jpg

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