Department of Orthopaedics, First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China; First Clinical Institute of Dalian Medical University, Dalian, People's Republic of China.
Department of Orthopaedics, First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China; First Clinical Institute of Dalian Medical University, Dalian, People's Republic of China.
J Clin Neurosci. 2022 May;99:89-93. doi: 10.1016/j.jocn.2022.01.011. Epub 2022 Mar 9.
This study aimed to retrospectively explore the relationship between facet tropism (FT) and cervical disc degeneration in cervical spondylotic radiculopathy (CSR) patients on 3-dimensional views. A total of 180 middle-aged patients with single-level CSR at C4/5 who underwent cervical CT and MRI in our hospital were included. The incidence of FT (or called FT (+), defined as FT ≥ 7 degree) at C3/4, C4/5, C5/6 levels were measured and calculated by reconstructed CT images on 3-dimensional views. The grade of cervical disc degeneration at three levels was assessed by MRI images by the method of Miyazali. Univariate analysis was performed to compare their cervical disc degeneration grade and CSR incidence between two groups stratified by FT (+). Moreover, a logistic regression model was used to investigate the association between FT (+) and grade of cervical disc degeneration and incidence of CSR adjusting for age, gender, and BMI. Grade of cervical disc degeneration and incidence of CSR in axial FT (+) group were both significantly increased compared to axial FT (-) group, while sagittal and coronal FT (+) groups showed no difference. Axial FT (+) was significantly associated with the grade of cervical disc degeneration and incidence of CSR. in middle-aged patients with CSR, axial FT (+) might be the risk factor for cervical disc degeneration but not sagittal and coronal FT (+). Also, axial FT (+) was positively associated with CSR incidence. Therefore, axial FT might play a vital role in the progression of cervical disc degeneration and CSR occurrence.
本研究旨在从三维视角回顾性探讨颈椎关节突关节（facet tropism，FT）偏斜与颈椎神经根型颈椎病（cervical spondylotic radiculopathy，CSR）患者颈椎间盘退变的关系。纳入我院行颈椎 CT 和 MRI 检查的 180 例单节段 CSR（C4/5 节段）的中年患者。通过三维重建 CT 图像测量并计算 C3/4、C4/5、C5/6 节段 FT（或称为 FT(+)，定义为 FT≥7 度）的发生率。通过 MRI 图像采用 Miyazali 方法评估三个节段的颈椎间盘退变程度。采用单因素分析比较 FT（+）和 FT（-）两组间颈椎间盘退变程度和 CSR 发生率的差异。此外，采用 Logistic 回归模型调整年龄、性别和 BMI 后，分析 FT（+）与颈椎间盘退变程度和 CSR 发生率的相关性。与轴向 FT（-）组相比，轴向 FT（+）组的颈椎间盘退变程度和 CSR 发生率均显著增加，而矢状面和冠状面 FT（+）组无差异。轴向 FT（+）与颈椎间盘退变程度和 CSR 发生率显著相关。在 CSR 的中年患者中，轴向 FT（+）可能是颈椎间盘退变的危险因素，但不是矢状面和冠状面 FT（+）。此外，轴向 FT（+）与 CSR 发生率呈正相关。因此，轴向 FT 可能在颈椎间盘退变和 CSR 发生的进展中发挥重要作用。
