Kim Youngmee, Cho Won-Kyung
Red Cross College of Nursing, Chung-Ang University, Seoul, Republic of Korea.
Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan, Seoul, Republic of Korea.
Tob Induc Dis. 2022 Feb 17;20:17. doi: 10.18332/tid/145698. eCollection 2022.
Adverse effects of smoking on kidney function have been demonstrated in both general populations and in populations with chronic kidney disease (CKD). Therefore, quitting smoking can have a significant impact on the mortality and disease progression of CKD. This study examined and compared factors associated with quitting status of smoking, in patients with and without CKD, among Korean adult male smokers, using the Korea National Health and Nutrition Examination Survey from 2008 to 2019, excluding 2013.
Wald test with multiple logistic regression was performed to investigate factors associated with quitting smoking in both CKD and non-CKD groups, along with the interaction effects between groups.
Of the 15747 eligible individuals, 909 had CKD, of whom 703 (weighted percentage: 74.4%) were quitters. In the non-CKD group, 8393 (weighted percentage: 50.4%) succeeded in quitting. Regular exercise was the only factor associated with quitting in both groups. The adjusted odd ratios with confidence intervals were 1.29 (95% CI: 1.17-1.42) and 2.84 (95% CI: 1.52-5.31) in the non-CKD and CKD groups, respectively (interaction p=0.0153). Unlike in the CKD group, marriage and higher systolic blood pressure were also associated with quitting, and lifetime smoking amount and secondhand smoke exposure at home were negatively associated with smoking cessation in the non-CKD group.
Exercise was the only factor associated with quitting smoking in the CKD group.
吸烟对肾功能的不良影响已在普通人群和慢性肾脏病（CKD）患者群体中得到证实。因此，戒烟对CKD患者的死亡率和疾病进展可能产生重大影响。本研究利用2008年至2019年（不包括2013年）的韩国国民健康与营养检查调查，对韩国成年男性吸烟者中患有和未患有CKD的患者戒烟状况相关因素进行了研究和比较。
采用多因素logistic回归的Wald检验，研究CKD组和非CKD组中与戒烟相关的因素以及两组之间的交互作用。
在15747名符合条件的个体中，909人患有CKD，其中703人（加权百分比：74.4%）已戒烟。在非CKD组中，8393人（加权百分比：50.4%）成功戒烟。规律运动是两组中唯一与戒烟相关的因素。非CKD组和CKD组经调整后的比值比及其置信区间分别为1.29（95%CI：1.17-1.42）和2.84（95%CI：1.52-5.31）（交互作用p=0.0153）。与CKD组不同，婚姻状况和较高的收缩压在非CKD组中也与戒烟有关，而非CKD组的终生吸烟量和在家中接触二手烟与戒烟呈负相关。
运动是CKD组中唯一与戒烟相关的因素。
