多发性骨髓瘤患者中出现爱泼斯坦-巴尔病毒黏膜皮肤溃疡后发生霍奇金淋巴瘤。
Epstein-Barr virus mucocutaneous ulcer followed by Hodgkin lymphoma in multiple myeloma patient.
作者信息
Forster Moriah, Fedoriw Yuri, Tuchman Sascha, Grover Natalie
机构信息
Department of Internal Medicine University of North Carolina Chapel Hill North Carolina USA.
Department of Pathology and Lab Medicine University of North Carolina Chapel Hill North Carolina USA.
出版信息
Clin Case Rep. 2022 Mar 3;10(3):e05528. doi: 10.1002/ccr3.5528. eCollection 2022 Mar.
Epstein-Barr virus mucocutaneous ulcers (EBV MCU) are B-cell lymphoproliferative disorders associated with immunosuppression. We report EBV MCU in a multiple myeloma patient on lenalidomide maintenance after stem cell transplant that resolved with decreased immunosuppression. Furthermore, the subsequent development of classical Hodgkin lymphoma suggests an underlying predisposition to EBV-driven lymphoproliferative disorders.
爱泼斯坦-巴尔病毒黏膜皮肤溃疡（EBV MCU）是与免疫抑制相关的B细胞淋巴增殖性疾病。我们报告了1例多发性骨髓瘤患者在干细胞移植后接受来那度胺维持治疗期间发生EBV MCU，随着免疫抑制的减轻而痊愈。此外，随后发生的经典型霍奇金淋巴瘤提示存在EBV驱动的淋巴增殖性疾病的潜在易感性。
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