腹部嗜铬细胞瘤术后复发转移的 CT 影像学特征及预测因素分析。
An Analysis of Computed Tomography Imaging Features and Predictive Factors for Postoperative Recurrence and Metastasis of Abdominal Paragangliomas.
机构信息
Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
出版信息
Contrast Media Mol Imaging. 2022 Feb 21;2022:8638588. doi: 10.1155/2022/8638588. eCollection 2022.
METHODS
We studied 51 abdominal PGL patients at the First Affiliated Hospital of Bengbu Medical College, Tongde Hospital, and Sir Run Shaw Hospital, Hangzhou, Zhejiang Province, China, from June 2009 to May 2019. Thereafter, the clinical research data, tumor biomarkers, and CT features were compared between the aggressive PGLs and the nonaggressive PGLs using independent-samples -tests and chi-square tests.
RESULTS
Of the 51 cases, 43 were benign and 8 had malignant tendencies. Postoperative recurrence and metastasis were more likely to occur when the tumor diameter was >8 cm or/and the enhancement degree was not obvious. Clinical symptoms, tumor markers, sex, age, and CT image characteristics including morphology, presence of cystic degeneration, "pointed peach" sign, calcification, hemorrhage, enlarged lymph nodes, and peritumor and intratumor blood vessels were not significantly different between the two groups ( > 0.05).
CONCLUSION
Our findings suggest that CT features, including size >8 cm and enhancement degree, could provide important evidence to assess risk factors for aggressive PGLs.
方法
本研究纳入了 2009 年 6 月至 2019 年 5 月于蚌埠医学院第一附属医院、同德医院和浙江大学附属邵逸夫医院就诊的 51 例腹型嗜铬细胞瘤患者。此后，采用独立样本 t 检验和卡方检验比较侵袭性 PGL 和非侵袭性 PGL 的临床研究数据、肿瘤标志物和 CT 特征。
结果
51 例患者中，43 例为良性，8 例具有恶性倾向。当肿瘤直径>8cm 或/和增强程度不明显时，更有可能发生术后复发和转移。两组间的临床症状、肿瘤标志物、性别、年龄、CT 图像特征（包括形态、囊变、“ pointed peach”征、钙化、出血、淋巴结肿大、肿瘤周围和肿瘤内血管）差异均无统计学意义（>0.05）。
结论
我们的研究结果表明，CT 特征（包括大小>8cm 和增强程度）可为评估侵袭性 PGL 的危险因素提供重要依据。
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