高流量与低流量鼻导管在减少支气管镜检查过程中低氧血症事件中的应用：一项系统评价和荟萃分析

High-Flow vs. Low-Flow Nasal Cannula in Reducing Hypoxemic Events During Bronchoscopic Procedures: A Systematic Review and Meta-Analysis.

作者信息

Sampsonas Fotios, Karamouzos Vasileios, Karampitsakos Theodoros, Papaioannou Ourania, Katsaras Matthaios, Lagadinou Maria, Zarkadi Eirini, Malakounidou Elli, Velissaris Dimitrios, Stratakos Grigorios, Tzouvelekis Argyrios

机构信息

Respiratory Medicine Department, University Hospital of Patras, Patras, Greece.

Intensive Care Unit, University Hospital of Patras, Patras, Greece.

出版信息

Front Med (Lausanne). 2022 Feb 24;9:815799. doi: 10.3389/fmed.2022.815799. eCollection 2022.

INTRODUCTION

High-flow nasal cannula (HFNC) oxygenation method has been proven to be successful in oxygenation of patients with respiratory failure and has exhibited clinical superiority compared to low-flow nasal cannula (LFNC).

METHODS

We performed a systematic review and meta-analysis to evaluate the potential favorable impact of HFNC oxygenation during bronchoscopy and related procedures like endobronchial ultrasound-transbronchial needle aspiration. Only randomized control trials (RCTs) were included in the meta-analysis.

RESULTS

Six randomized control trials with 1,170 patients were included in this meta-analysis. Patients who underwent bronchoscopy with the use of high-flow nasal cannula experienced less hypoxemic events/desaturations, less procedural interruptions and pneumothoraxes compared to patients under low-flow nasal cannula treatment. This beneficial effect of HFNC in hypoxemic events was persistent 10 min after the end of procedure.