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冠状动脉旁路移植术后抗血小板治疗-临床实践的不均衡。

ANTIPLATELET THERAPY AFTER CORONARY ARTERY BYPASS GRAFT SURGERY - UNEVENNESS OF DAILY CLINICAL PRACTICE.

机构信息

1Krapinske Toplice Special Hospital for Medical Rehabilitation, Krapinske Toplice, Croatia; 2Faculty of Medicine in Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 3Faculty of Dental Medicine and Health in Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 4Zagreb University Hospital Centre, Zagreb, Croatia; 5School of Medicine, University of Zagreb, Zagreb, Croatia.

出版信息

Acta Clin Croat. 2022 Feb;60(3):540-543. doi: 10.20471/acc.2021.60.03.26.

DOI:10.20471/acc.2021.60.03.26
PMID:35282474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8907948/
Abstract

Antiplatelet therapy is an integral part of optimal medicamentous therapy in patients with coronary artery disease. The strategy of antiplatelet/anticoagulant therapy is adjusted (combination of drugs, dosing and duration of therapy) depending on the stage of the disease (acute coronary syndrome with percutaneous coronary intervention, chronic coronary syndrome, or coronary surgical revascularization) and comorbidity of each patient (e.g., atrial fibrillation, left ventricular thrombus, etc.). Guidelines and clinical practice in particular are not uniform and specific regarding dual antiplatelet therapy in patients undergoing coronary artery bypass grafting, especially in the setting of chronic coronary syndrome.

摘要

抗血小板治疗是冠状动脉疾病患者最佳药物治疗的重要组成部分。抗血小板/抗凝治疗策略(药物组合、剂量和治疗持续时间)取决于疾病阶段(经皮冠状动脉介入治疗的急性冠状动脉综合征、慢性冠状动脉综合征或冠状动脉搭桥手术)和每位患者的合并症(例如,心房颤动、左心室血栓等)。指南和临床实践在接受冠状动脉旁路移植术的患者中尤其在慢性冠状动脉综合征患者中,关于双联抗血小板治疗的具体细节并不统一。

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Arch Med Sci Atheroscler Dis. 2025 Mar 20;10:e16-e27. doi: 10.5114/amsad/202297. eCollection 2025.
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Antithrombotic strategies for preventing graft failure in coronary artery bypass graft.抗血栓策略在预防冠状动脉旁路移植中移植物失败的应用。
J Thromb Thrombolysis. 2024 Apr;57(4):547-557. doi: 10.1007/s11239-023-02940-5. Epub 2024 Mar 16.

本文引用的文献

1
Antiplatelet Therapy and Coronary Artery Bypass Grafting: Analysis of Current Evidence With a Focus on Acute Coronary Syndrome.抗血小板治疗与冠状动脉旁路移植术:急性冠状动脉综合征相关当前证据分析。
Can J Cardiol. 2019 Aug;35(8):1030-1038. doi: 10.1016/j.cjca.2019.06.003. Epub 2019 Jun 11.
2
Network meta-analysis of antiplatelet therapy following coronary artery bypass grafting (CABG): none versus one versus two antiplatelet agents.冠状动脉旁路移植术(CABG)后抗血小板治疗的网络荟萃分析:无抗血小板药物与一种抗血小板药物与两种抗血小板药物的比较
Ann Cardiothorac Surg. 2018 Sep;7(5):577-585. doi: 10.21037/acs.2018.09.02.
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Dual versus single antiplatelet therapy after coronary artery bypass graft surgery: An updated meta-analysis.冠状动脉旁路移植术后双联与单联抗血小板治疗:更新的荟萃分析。
Int J Cardiol. 2018 Oct 15;269:80-88. doi: 10.1016/j.ijcard.2018.07.083. Epub 2018 Jul 19.
4
2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS: The Task Force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and of the European Association for Cardio-Thoracic Surgery (EACTS).2017年欧洲心脏病学会(ESC)与欧洲心胸外科学会(EACTS)合作制定的冠状动脉疾病双联抗血小板治疗重点更新:欧洲心脏病学会(ESC)和欧洲心胸外科学会(EACTS)冠状动脉疾病双联抗血小板治疗特别工作组。
Eur Heart J. 2018 Jan 14;39(3):213-260. doi: 10.1093/eurheartj/ehx419.
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2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC).2017年欧洲心脏病学会(ESC)ST段抬高型急性心肌梗死患者管理指南:欧洲心脏病学会(ESC)ST段抬高型急性心肌梗死患者管理工作组
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2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.2016美国心脏病学会/美国心脏协会关于冠状动脉疾病患者双联抗血小板治疗持续时间的指南聚焦更新:美国心脏病学会/美国心脏协会临床实践指南工作组报告
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Circulation. 2015 Mar 10;131(10):927-64. doi: 10.1161/CIR.0000000000000182. Epub 2015 Feb 9.
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Effect of clopidogrel use post coronary artery bypass surgery on graft patency.氯吡格雷在冠状动脉旁路手术后对桥血管通畅性的影响。
Ann Thorac Surg. 2014 Jan;97(1):15-21. doi: 10.1016/j.athoracsur.2013.08.058. Epub 2013 Nov 6.
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Aspirin plus clopidogrel for optimal platelet inhibition following off-pump coronary artery bypass surgery: results from the CRYSSA (prevention of Coronary arteRY bypaSS occlusion After off-pump procedures) randomised study.阿司匹林联合氯吡格雷在非体外循环冠状动脉旁路移植术后的最佳血小板抑制作用:CRYSSA(非体外循环手术后冠状动脉旁路阻塞的预防)随机研究结果。
Heart. 2012 Dec;98(23):1710-5. doi: 10.1136/heartjnl-2012-302449. Epub 2012 Sep 2.