Tombolini Beatrice, Cavalleri Michele, Sacconi Riccardo, Querques Lea, Zucchiatti Ilaria, Bandello Francesco, Querques Giuseppe
School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Division of Head and Neck, Ophthalmology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Am J Ophthalmol Case Rep. 2022 Mar 5;26:101472. doi: 10.1016/j.ajoc.2022.101472. eCollection 2022 Jun.
To report a case of progressive resolution of exudation in a patient affected by perifoveal vascular anomalous complex (PVAC) undergoing topical diclofenac therapy.
A 74-year-old man presented to our department with visual decrease in his right eye lasting six months. Lack of clinical history of arterial hypertension, diabetes, or any other systemic or local vasculopathy, together with retinal multimodal imaging, led to the diagnosis of exudative (e)PVAC. Serial spectral-domain optical coherence tomography (SD-OCT) examinations documented a resolution of intraretinal exudation after one-month topical diclofenac therapy.
Initiation of topical diclofenac was associated with resolution of exudation, therefore we hypothesize its potential role in the treatment of ePVAC.
报告一例接受双氯芬酸局部治疗的中心凹周围血管异常复合体（PVAC）患者渗出逐渐消退的病例。
一名74岁男性因右眼视力下降6个月前来我科就诊。缺乏动脉高血压、糖尿病或任何其他全身性或局部血管病变的临床病史，结合视网膜多模态成像，诊断为渗出性（e）PVAC。连续的光谱域光学相干断层扫描（SD-OCT）检查记录了双氯芬酸局部治疗1个月后视网膜内渗出的消退情况。
双氯芬酸局部治疗与渗出消退相关，因此我们推测其在ePVAC治疗中的潜在作用。
