Varma Prem P, Bajpai Geet
Department of Nephrology, Venkateshwar Hospital, Dwarka, New Delhi, India.
Indian J Nephrol. 2022 Jan-Feb;32(1):87-89. doi: 10.4103/ijn.IJN_330_20. Epub 2022 Jan 5.
Most cases of Baclofen toxicity have been reported in patients with impaired kidney functions, within a few days to weeks after ingestion. We report three cases of Baclofen induced encephalopathy in chronic kidney disease patients; two developed encephalopathy within 6-8 h after ingestion of a single tablet and third on 4 day of consuming 2.5 mg twice daily dose. All three cases recovered fully following haemodialysis treatment.
大多数巴氯芬中毒病例报告于肾功能受损的患者，在摄入药物后的数天至数周内。我们报告了3例慢性肾病患者中巴氯芬诱发的脑病；2例在单次服用一片药物后的6 - 8小时内出现脑病，第3例在每日两次服用2.5毫克剂量的第4天出现脑病。所有3例患者在接受血液透析治疗后均完全康复。
