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腹腔内压力与腹膜假黏液瘤术后热灌注化疗耐受性的相关性

The Correlation Between Intra-Abdominal Pressure and Tolerance to Postoperative Hyperthermic Intraperitoneal Chemotherapy for Pseudomyxoma Peritonei.

作者信息

Yu Junye, Yu Lifei, Su Lin, Shi Ying

机构信息

Department of Nursing, Aerospace Center Hospital, Beijing, China.

Department of Myxoma, Aerospace Center Hospital, Beijing, China.

出版信息

Front Surg. 2022 Feb 25;9:797811. doi: 10.3389/fsurg.2022.797811. eCollection 2022.

DOI:10.3389/fsurg.2022.797811
PMID:35284489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8916238/
Abstract

OBJECTIVE

To evaluate the correlation between pain intensity and comfort level in patients with pseudomyxoma peritoneum (PMP) before and after hyperthermic intraperitoneal chemotherapy (HIPEC).

METHODS

From June 2018 to June 2019, patients who underwent HIPEC for PMP after surgical treatment in our institute were selected. The intra-abdominal pressure (IAP) and pain intensity (PI) before and after HIPEC were recorded, and the correlation between them was analyzed.

RESULTS

Seventy-four patients received HIPEC 253 times. IAP and PI were significantly higher after perfusion than before perfusion ( < 0.05). When IAP < 12 cmHO, the change of PI was not correlated to the increase of IAP, and the patient tolerated the treatment. However, when IAP > 12 cmHO, the increase of PI was significantly associated with IAP and cause significant discomfort during the treatment.

CONCLUSION

IAP may be a monitoring index for the comfort of PMP patients during the postoperative HIPEC treatment.

摘要

目的

评估腹膜假黏液瘤（PMP）患者在热灌注化疗（HIPEC）前后疼痛强度与舒适度之间的相关性。

方法

选取2018年6月至2019年6月在我院接受手术治疗后行HIPEC的PMP患者。记录HIPEC前后的腹腔内压力（IAP）和疼痛强度（PI），并分析两者之间的相关性。

结果

74例患者接受HIPEC共253次。灌注后IAP和PI均显著高于灌注前（<0.05）。当IAP<12 cmH₂O时，PI的变化与IAP的升高无关，患者能耐受治疗。然而，当IAP>12 cmH₂O时，PI的升高与IAP显著相关，并在治疗期间引起明显不适。

结论

IAP可能是PMP患者术后HIPEC治疗舒适度的监测指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4735/8916238/bf6e0d8b924b/fsurg-09-797811-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4735/8916238/d562545804f5/fsurg-09-797811-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4735/8916238/d685b4f6e6f2/fsurg-09-797811-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4735/8916238/4d03cd35307a/fsurg-09-797811-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4735/8916238/bf6e0d8b924b/fsurg-09-797811-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4735/8916238/d562545804f5/fsurg-09-797811-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4735/8916238/d685b4f6e6f2/fsurg-09-797811-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4735/8916238/4d03cd35307a/fsurg-09-797811-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4735/8916238/bf6e0d8b924b/fsurg-09-797811-g0004.jpg

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