Abe Niichiro, Baba Takashi, Nakamura Yoshitaka, Murakami Shintaro
Division of Microbiology, Osaka Institute of Public Health, 8-34 Tojo-cho, Tennoji-ku, Osaka, 543-0026, Japan.
Department of Pediatrics, Kansai Medical University, 2-5-1 Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Curr Res Parasitol Vector Borne Dis. 2021 Jul 21;1:100042. doi: 10.1016/j.crpvbd.2021.100042. eCollection 2021.
The cestode (syns. and ), the broad fish tapeworm, is a parasitic agent of intestinal infection acquired by consumption of raw or undercooked Pacific salmon, spp. Sequencing studies conducted about a decade ago revealed the presence of two major lineages (A and B) in the broad fish tapeworm population within Asian coastal areas. However, in spite of the accumulation of sequence data on GenBank recently, no further genetic analyses of have been attempted. The present study assessed for the first time the global 1 variation in . Novel partial 1 sequences of 14 isolates of from 12 patients were generated, and a global genetic analysis was performed using the 14 novel and 79 previously published sequences for isolates from definitive and second intermediate hosts of this species was performed. A total of 48 haplotypes of three haplotype groups (Types A, B and C) were identified, and co-infections with genetically different were highlighted in humans and Pacific salmon.
绦虫（同义词： 及 ），即阔节裂头绦虫，是一种因食用生的或未煮熟的太平洋鲑鱼（ 属）而导致肠道感染的寄生虫。大约十年前进行的测序研究表明，亚洲沿海地区的阔节裂头绦虫种群中存在两个主要谱系（A和B）。然而，尽管最近GenBank上积累了序列数据，但尚未对阔节裂头绦虫进行进一步的遗传分析。本研究首次评估了阔节裂头绦虫的全球1变异情况。生成了来自12名患者的14株阔节裂头绦虫的新型部分1序列，并使用这14个新序列和79个先前发表的该物种终末宿主和第二中间宿主分离株的序列进行了全球遗传分析。共鉴定出三个单倍型组（A、B和C型）的48个单倍型，并强调了人类和太平洋鲑鱼中存在基因不同的阔节裂头绦虫共感染情况。
