Department of Dermatology, KCU-GME Advanced Dermatology and Cosmetic Surgery, Oviedo, FL, USA.
Clin Toxicol (Phila). 2022 Jul;60(7):882-883. doi: 10.1080/15563650.2022.2048004. Epub 2022 Mar 14.
Levamisole is a commonly utilized adulterant for illicit drugs such as cocaine. It has been associated with perinuclear anti-neutrophil cytoplasmic antibody (P-ANCA)-associated retiform purpura in cocaine users. It is important for clinicians to recognize the typical location and clinical presentation of these patients to reach a proper diagnosis. We present a severe case of levamisole-induced vasculitis in a cocaine user to highlight the classic clinical findings and the diagnostic evaluation for these patients.
左旋咪唑是一种常用于可卡因等非法药物的掺杂物。它与可卡因使用者的核周抗中性粒细胞胞浆抗体(P-ANCA)相关的网状紫癜有关。对于临床医生来说,识别这些患者的典型位置和临床表现以做出正确诊断非常重要。我们报告了一例可卡因使用者中严重的左旋咪唑诱导性血管炎病例,以强调这些患者的典型临床发现和诊断评估。