Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Show Chwan Hospital, Taipei, Taiwan.
Int J Hyperthermia. 2022;39(1):485-489. doi: 10.1080/02656736.2022.2039788.
This retrospective study used data from patients treated for uterine fibroids with ultrasound-guided high-intensity focused ultrasound (USgHIFU) from April 2015 to April 2019. One hundred and seven patients with solitary fibroids were divided into two groups: (1) the L group with larger fibroids (≥10 cm) and (2) the S group with smaller fibroids (<10 cm). Using magnetic resonance imaging (MRI), we examined the efficacy of high-intensity focused ultrasound (HIFU) ablation by comparing uterine and fibroid volumes before and three months after the procedure. The three-month follow-up clinical visit used a visual analog scale and a uterine fibroid symptom health-related quality of life questionnaire to evaluate clinical symptoms. Both the L and S groups had significant reduction in uterine and fibroid volumes, but the rate was significantly higher in the S group ( < 0.05). Both groups also had improvements in clinical symptoms, but there was no statistical difference. USgHIFU reduced the size of both large and small fibroids but was most effective on fibroids smaller than 10 cm. Both the L and S groups had improved dysmenorrhea symptoms and quality of life.
这项回顾性研究使用了 2015 年 4 月至 2019 年 4 月接受超声引导高强度聚焦超声（USgHIFU）治疗的子宫肌瘤患者的数据。107 名单发子宫肌瘤患者被分为两组：（1）L 组肌瘤较大（≥10cm），（2）S 组肌瘤较小（<10cm）。使用磁共振成像（MRI），我们通过比较术前和术后三个月子宫和肌瘤体积来检查高强度聚焦超声（HIFU）消融的效果。术后三个月的临床随访使用视觉模拟评分和子宫肌瘤症状健康相关生活质量问卷来评估临床症状。L 组和 S 组的子宫和肌瘤体积均显著减少，但 S 组的减少率明显更高（<0.05）。两组的临床症状也都有所改善，但无统计学差异。USgHIFU 可缩小大小肌瘤的体积，但对小于 10cm 的肌瘤效果最明显。L 组和 S 组的痛经症状和生活质量均有所改善。
