Elsisy Mohamed F, Schaff Hartzell V, Crestanello Juan A, Alkhouli Mohamad A, Stulak John M, Stephens Elizabeth H
Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
J Card Surg. 2022 Jun;37(6):1664-1670. doi: 10.1111/jocs.16396. Epub 2022 Mar 14.
While advanced age can be considered by some a contraindication to open-heart surgery, there is a paucity of data regarding outcomes of cardiac surgery in nonagenarians. We, therefore, sought to investigate the outcomes of nonagenarians undergoing cardiac surgery.
A retrospective review of our institutional Society of Thoracic Surgeons database between 1993 and 2019 was performed. Among a total of 32,421 patients who underwent open-heart surgery, 134 patients (0.4%) were nonagenarians (50.7% females, median age 91.6 [interquartile range: 90.7-92.9]). A comparison was performed between nonagenarians and patients aged 80-89 years. A regression analysis was performed to evaluate factors associated with midterm mortality in nonagenarians.
The incidence of cardiac surgery in nonagenarians has been stable over time, from 0.4% in (1993-2000), 0.5% in (2001-2010) to 0.4% in (2011-2019). Valve surgery and CABG+valve were higher in nonagenarians compared to octogenarians (44.8% vs. 25.6%, 39.6% vs. 30.7%, respectively), but CABG was lower (15.7% vs. 33.8%); p < .01. Urgent/emergent surgery status was similar between groups (p = .7). Operative mortality was similar in the two groups (6% vs. 4.6%, p = .5). Hospital complications were comparable between groups.
Cardiac surgery in nonagenarians can be achieved with acceptable morbidity and mortality. This study can be a benchmark for risk stratification for cardiac surgery in this high-risk population.
虽然高龄可能被一些人视为心脏直视手术的禁忌证,但关于九旬老人心脏手术结果的数据却很匮乏。因此,我们试图研究九旬老人接受心脏手术的结果。
对我们机构1993年至2019年的胸外科医师协会数据库进行回顾性研究。在总共32421例接受心脏直视手术的患者中,134例(0.4%)为九旬老人(女性占50.7%,中位年龄91.6岁[四分位间距:90.7 - 92.9岁])。对九旬老人与80 - 89岁患者进行了比较。进行回归分析以评估与九旬老人中期死亡率相关的因素。
随着时间推移,九旬老人心脏手术的发生率一直稳定,从1993 - 2000年的0.4%,2001 - 2010年的0.5%到2011 - 2019年的0.4%。与八旬老人相比,九旬老人的瓣膜手术和冠状动脉旁路移植术(CABG)+瓣膜手术比例更高(分别为44.8%对25.6%,39.6%对30.7%),但单纯CABG手术比例较低(15.7%对33.8%);p < 0.01。两组间急诊/紧急手术状态相似(p = 0.7)。两组手术死亡率相似(6%对4.6%,p = 0.5)。两组间医院并发症情况相当。
九旬老人进行心脏手术可获得可接受的发病率和死亡率。本研究可为这一高危人群心脏手术的风险分层提供基准。