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北塞浦路斯土耳其共和国儿童无症状 SARS-CoV-2 IgG 血清阳性率。

The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus.

机构信息

Department of Medical Microbiology and Clinical Microbiology, Near East University, Nicosia, Cyprus.

Department of Paediatrics, Near East University, Nicosia, Cyprus.

出版信息

Turk J Pediatr. 2022;64(1):179-185. doi: 10.24953/turkjped.2021.1330.

Abstract

BACKGROUND

While children were initially thought to have serious contributions to the coronavirus disease 2019 (COVID-19) transmission, recent studies suggest otherwise. However, the possible effect of asymptomatic pediatric spread still has not yet received enough attention. The aim of our study was to estimate asymptomatic infection rates among children in the Turkish Republic of Northern Cyprus, by using pediatric patients admitted to a university hospital without any COVID-19-associated symptoms.

METHODS

Blood samples collected from 80 pediatric patients with no symptoms and history of COVID-19 infection, who were admitted to a university hospital between September 2020 and January 2021, were included in the retrospective study. Isolated serum samples were tested by Dia.Pro SARS-CoV-2 IgG ELISA assays.

RESULTS

The patient group included 40 (50%) male and 40 (50%) female patients. The average age of children was 7.6 ± 4.0 years, with min-max ages ranging from 2 to 15 years. Among the 80 patients tested, only one (1.3%) was detected positive by the Dia.Pro IgG ELISA kit.

CONCLUSIONS

The asymptomatic seropositivity reported in our study suggests the use of randomly performed serologic tests to monitor SARS-CoV-2 infection among the pediatric population in schools that would contribute to the public health fight against COVID-19.

摘要

背景

虽然最初认为儿童对 2019 年冠状病毒病(COVID-19)的传播有严重的影响,但最近的研究表明并非如此。然而,无症状儿科传播的可能影响尚未得到足够重视。我们的研究目的是通过对没有任何 COVID-19 相关症状而被大学医院收治的儿科患者进行研究,来估计北塞浦路斯土耳其共和国儿童的无症状感染率。

方法

我们对 2020 年 9 月至 2021 年 1 月期间在一所大学医院住院且无 COVID-19 感染史的 80 名无任何症状的儿科患者采集血样,进行了回顾性研究。使用 Dia.Pro SARS-CoV-2 IgG ELISA 检测试剂盒检测分离的血清样本。

结果

患者组包括 40 名(50%)男性和 40 名(50%)女性患者。儿童的平均年龄为 7.6 ± 4.0 岁,年龄范围为 2 至 15 岁。在 80 名接受检测的患者中,只有 1 名(1.3%)通过 Dia.Pro IgG ELISA 试剂盒检测呈阳性。

结论

我们的研究报告的无症状血清阳性率表明,应在学校随机进行血清学检测,以监测儿科人群中的 SARS-CoV-2 感染,这将有助于对抗 COVID-19 的公共卫生斗争。

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