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术后早期疼痛缓解与肩关节置换术后长期功能改善相关:一项回顾性病例系列研究。

Early reduction in postoperative pain is associated with improved long-term function after shoulder arthroplasty: a retrospective case series.

机构信息

Department of Orthopedic Surgery, Prisma Health - Upstate, Greenville, SC, USA.

College of Medicine, University of Florida, Gainesville, FL, USA.

出版信息

Eur J Orthop Surg Traumatol. 2023 May;33(4):1023-1030. doi: 10.1007/s00590-022-03242-x. Epub 2022 Mar 14.

Abstract

PURPOSE

Mixed modalities are frequently utilized in total shoulder arthroplasty (TSA) to control pain, improve patient satisfaction, reduce narcotics use and facilitate earlier discharge. We investigate the relationship between early postoperative pain control and long-term functional outcomes after shoulder arthroplasty.

METHODS

A retrospective review identified 294 patients (314 shoulders) who underwent anatomic or reverse TSA and received a continuous cervical paravertebral nerve block perioperatively. Opioid and non-opioid analgesics were also available to the patients in an "as needed" capacity to augment perioperative pain control. In addition to demographic and surgical characteristics, the impact on functional outcomes of relative pain (i.e., a patient's subjective pain relative to the entire cohort), pain gradient (i.e., the slope of a patient's subjective pain), and opioid consumption during the first 24 h postoperatively were assessed. Shoulder function was assessed using validated outcome measures collected at 2 year follow-up. Outcomes were measured using American Shoulder and Elbow Surgeons questionnaire (ASES), Shoulder Pain and Disability Index (SPADI), SPADI-130, Raw and Normalized Constant Score, SST-12 and UCLA score.

RESULTS

Patients younger than 65, females, reverse TSA, revisions, and preoperative opioid users had worse functional outcomes. On univariate analysis, increased pain perioperatively (> 50% percentile relative pain) was associated with decreased function at 2 years when analyzed with all seven outcome scores (P < .001 for all), reaching minimal clinically important difference (MCID) using the Constant Score. On multivariate analysis, increased pain in the first 24 h postoperatively (assessed on a continuous scale) was independently associated with worse ASES, SPADI, and SPADI-130 scores. Intraoperative ketamine administration and opioid consumption in the 24 h postoperative period did not influence long-term shoulder function.

CONCLUSION

Patients reporting reduced pain after TSA demonstrated improved shoulder function with the Constant score at 2 years postoperatively in both univariate and multivariate analysis. Larger-scale investigation may be warranted to see if this is true for other functional outcome measures.

LEVEL OF EVIDENCE

III, treatment study.

摘要

目的

在全肩关节置换术(TSA)中,常采用混合疗法来控制疼痛、提高患者满意度、减少阿片类药物的使用并促进更早出院。我们研究了肩关节置换术后早期疼痛控制与长期功能结果之间的关系。

方法

回顾性研究确定了 294 例(314 肩)接受解剖或反向 TSA 并接受围手术期连续颈椎旁神经阻滞的患者。还为患者提供了阿片类药物和非阿片类药物镇痛剂,以按需增强围手术期疼痛控制。除了人口统计学和手术特征外,相对疼痛(即患者的主观疼痛相对于整个队列)、疼痛梯度(即患者主观疼痛的斜率)以及术后 24 小时内阿片类药物的使用对功能结果的影响也进行了评估。使用经过验证的 2 年随访时收集的结果测量指标评估肩部功能。使用美国肩肘外科医师协会问卷(ASES)、肩痛和残疾指数(SPADI)、SPADI-130、原始和归一化常数评分、SST-12 和 UCLA 评分来测量结果。

结果

年龄小于 65 岁、女性、反向 TSA、翻修术和术前使用阿片类药物的患者功能结果更差。在单变量分析中,当使用所有七种结果评分进行分析时,围手术期疼痛增加(相对疼痛超过 50%分位数)与 2 年时的功能下降相关(所有评分均<.001),使用常数评分达到了最小临床重要差异(MCID)。在多变量分析中,术后 24 小时内的疼痛增加(以连续量表评估)与 ASES、SPADI 和 SPADI-130 评分的降低独立相关。术中给予氯胺酮和术后 24 小时内阿片类药物的使用并不影响肩部的长期功能。

结论

在 TSA 后报告疼痛减轻的患者中,在术后Constant 评分中,2 年时的肩部功能得到了改善,在单变量和多变量分析中均如此。可能需要更大规模的调查,以确定这是否适用于其他功能结果测量指标。

证据等级

III 级,治疗研究。

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