Faculty of Science and Technology, Kochi University, 2-5-1 Akebono-cho, Kochi, 780-8520, Japan.
Advanced Science Research Center, Japan Atomic Energy Agency (JAEA), 2-4 Shirakata, Tokai-mura, Ibaraki, 319-1195, Japan.
Anal Sci. 2022 Mar;38(3):563-569. doi: 10.1007/s44211-022-00066-x. Epub 2022 Feb 17.
A zirconia (ZrO) stationary phase with a chemically fixed silane coupling agent (trimethyl [3-(trimethoxysilyl)propyl]ammonium chloride; TMA), which possesses quaternary ammonium functional groups, is evaluated as a separation column for ion chromatography (IC) of anions. The selectivity for anions varies depending on the amount of TMA immobilized on the ZrO. The TMA-ZrO, with an anion-exchange capacity of 17 ± 3 µeq/g, shows an anion-exchange reaction that involves the specific retention of fluoride ion on ZrO. The TMA-ZrO exhibits a decrease of the anion resolution with an increase of the eluent pH and an enhancement of the selective separation of fluoride ion with an increase of the column temperature. Through this study, the TMA-ZrO stationary phase shows potential as a new medium for ion separation.
一种具有化学固定的硅烷偶联剂（三甲基[3-（三甲氧基硅基）丙基]氯化铵；TMA）的氧化锆（ZrO）固定相，具有季铵官能团，被评估为用于阴离子离子色谱（IC）的分离柱。阴离子的选择性取决于固定在 ZrO 上的 TMA 的量。TMA-ZrO 的阴离子交换容量为 17 ± 3 µeq/g，表现出涉及氟离子在 ZrO 上的特定保留的阴离子交换反应。TMA-ZrO 随着洗脱液 pH 的增加，阴离子分辨率降低，随着柱温的升高，氟离子的选择性分离增强。通过这项研究，TMA-ZrO 固定相显示出作为离子分离新介质的潜力。
