Touchstone Diabetes Center, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
Department of Cell Biology, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
Nat Metab. 2022 Mar;4(3):305-307. doi: 10.1038/s42255-022-00541-9.
Healthy white adipose tissue is dependent on proliferation of endothelial cells to maintain homeostasis or undergo expansion. A new study shows that endothelial cells communicate with adipocytes via polyamines to promote vascularization of adipose tissue, thereby reversing the metabolic effects of obesity.
健康的白色脂肪组织依赖于内皮细胞的增殖来维持其体内平衡或进行扩张。一项新的研究表明,内皮细胞通过多胺与脂肪细胞进行通讯,以促进脂肪组织的血管生成,从而逆转肥胖的代谢效应。