School of Public Health, University of Sydney, Sydney, NSW, Australia and.
School of Public Health, University of Technology Sydney, Sydney, NSW, Australia.
Int J Epidemiol. 2022 Jun 13;51(3):718-726. doi: 10.1093/ije/dyac032.
To assess whether the observed numbers and seasonality of deaths in Australia during 2020 differed from expected trends based on 2015-19 data.
We used provisional death data from the Australian Bureau of Statistics, stratified by state, age, sex and cause of death. We compared 2020 deaths with 2015-19 deaths using interrupted time series adjusted for time trend and seasonality. We measured the following outcomes along with 95% confidence intervals: observed/expected deaths (rate ratio: RR), change in seasonal variation in mortality (amplitude ratio: AR) and change in week of peak seasonal mortality (phase difference: PD).
Overall 4% fewer deaths from all causes were registered in Australia than expected in 2020 [RR 0·96 (0·95-0·98)] with reductions across states, ages and sex strata. There were fewer deaths from respiratory illness [RR 0·79 (0·76-0·83)] and dementia [RR 0·95 (0·93-0·98)] but more from diabetes [RR 1·08 (1·04-1·13)]. Seasonal variation was reduced for deaths overall [AR 0·94 (0·92-0·95)], and for deaths due to respiratory illnesses [AR 0·78 (0·74-0·83)], dementia [AR 0.92 (0.89-0.95)] and ischaemic heart disease [0.95 (0.90-0.97)].
The observed reductions in respiratory and dementia deaths and the reduced seasonality in ischaemic heart disease deaths may reflect reductions in circulating respiratory (non-SARS-CoV-2) pathogens resulting from the public health measures taken in 2020. The observed increase in diabetes deaths is unexplained and merits further study.
评估 2020 年澳大利亚的死亡人数和季节性是否与基于 2015-19 年数据的预期趋势存在差异。
我们使用澳大利亚统计局的临时死亡数据,按州、年龄、性别和死因进行分层。我们使用时间趋势和季节性调整的中断时间序列比较了 2020 年的死亡人数和 2015-19 年的死亡人数。我们测量了以下结果及其 95%置信区间:观察到的/预期的死亡人数(比率比:RR)、死亡率季节性变化的变化(幅度比:AR)和季节性死亡高峰周的变化(相位差:PD)。
2020 年澳大利亚的总死亡人数比预期减少了 4%[RR 0.96(0.95-0.98)],各州、各年龄段和各性别群体均有减少。死于呼吸道疾病的人数减少[RR 0.79(0.76-0.83)]和痴呆症[RR 0.95(0.93-0.98)],但死于糖尿病的人数增加[RR 1.08(1.04-1.13)]。总的死亡人数的季节性变化减少[AR 0.94(0.92-0.95)],死于呼吸道疾病的死亡人数的季节性变化减少[AR 0.78(0.74-0.83)],死于痴呆症的死亡人数的季节性变化减少[AR 0.92(0.89-0.95)],死于缺血性心脏病的死亡人数的季节性变化减少[0.95(0.90-0.97)]。
观察到呼吸道疾病和痴呆症死亡人数的减少,以及缺血性心脏病死亡人数季节性的减少,可能反映了 2020 年采取的公共卫生措施减少了循环中的呼吸道(非 SARS-CoV-2)病原体。观察到的糖尿病死亡人数增加的原因尚不清楚,值得进一步研究。