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从大流行病中学习:2020 年澳大利亚的死亡率趋势和季节性死亡。

Learning from the pandemic: mortality trends and seasonality of deaths in Australia in 2020.

机构信息

School of Public Health, University of Sydney, Sydney, NSW, Australia and.

School of Public Health, University of Technology Sydney, Sydney, NSW, Australia.

出版信息

Int J Epidemiol. 2022 Jun 13;51(3):718-726. doi: 10.1093/ije/dyac032.

Abstract

AIM

To assess whether the observed numbers and seasonality of deaths in Australia during 2020 differed from expected trends based on 2015-19 data.

METHODS

We used provisional death data from the Australian Bureau of Statistics, stratified by state, age, sex and cause of death. We compared 2020 deaths with 2015-19 deaths using interrupted time series adjusted for time trend and seasonality. We measured the following outcomes along with 95% confidence intervals: observed/expected deaths (rate ratio: RR), change in seasonal variation in mortality (amplitude ratio: AR) and change in week of peak seasonal mortality (phase difference: PD).

RESULTS

Overall 4% fewer deaths from all causes were registered in Australia than expected in 2020 [RR 0·96 (0·95-0·98)] with reductions across states, ages and sex strata. There were fewer deaths from respiratory illness [RR 0·79 (0·76-0·83)] and dementia [RR 0·95 (0·93-0·98)] but more from diabetes [RR 1·08 (1·04-1·13)]. Seasonal variation was reduced for deaths overall [AR 0·94 (0·92-0·95)], and for deaths due to respiratory illnesses [AR 0·78 (0·74-0·83)], dementia [AR 0.92 (0.89-0.95)] and ischaemic heart disease [0.95 (0.90-0.97)].

CONCLUSIONS

The observed reductions in respiratory and dementia deaths and the reduced seasonality in ischaemic heart disease deaths may reflect reductions in circulating respiratory (non-SARS-CoV-2) pathogens resulting from the public health measures taken in 2020. The observed increase in diabetes deaths is unexplained and merits further study.

摘要

目的

评估 2020 年澳大利亚的死亡人数和季节性是否与基于 2015-19 年数据的预期趋势存在差异。

方法

我们使用澳大利亚统计局的临时死亡数据,按州、年龄、性别和死因进行分层。我们使用时间趋势和季节性调整的中断时间序列比较了 2020 年的死亡人数和 2015-19 年的死亡人数。我们测量了以下结果及其 95%置信区间:观察到的/预期的死亡人数(比率比:RR)、死亡率季节性变化的变化(幅度比:AR)和季节性死亡高峰周的变化(相位差:PD)。

结果

2020 年澳大利亚的总死亡人数比预期减少了 4%[RR 0.96(0.95-0.98)],各州、各年龄段和各性别群体均有减少。死于呼吸道疾病的人数减少[RR 0.79(0.76-0.83)]和痴呆症[RR 0.95(0.93-0.98)],但死于糖尿病的人数增加[RR 1.08(1.04-1.13)]。总的死亡人数的季节性变化减少[AR 0.94(0.92-0.95)],死于呼吸道疾病的死亡人数的季节性变化减少[AR 0.78(0.74-0.83)],死于痴呆症的死亡人数的季节性变化减少[AR 0.92(0.89-0.95)],死于缺血性心脏病的死亡人数的季节性变化减少[0.95(0.90-0.97)]。

结论

观察到呼吸道疾病和痴呆症死亡人数的减少,以及缺血性心脏病死亡人数季节性的减少,可能反映了 2020 年采取的公共卫生措施减少了循环中的呼吸道(非 SARS-CoV-2)病原体。观察到的糖尿病死亡人数增加的原因尚不清楚,值得进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7411/9189967/2ecdcf4e3113/dyac032f1.jpg

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