Medical School, University of Thessaly, 415 00 Larissa, Greece.
Department of Medical Oncology, Metaxa Cancer Hospital, 185 37 Athens, Greece.
Rev Recent Clin Trials. 2022;17(2):73-85. doi: 10.2174/1574887117666220314161609.
Women undergoing mastectomy choose to pursue breast reconstruction (BR) in order to reduce their body image distress.Adjuvant chest wall irradiation is associated with a negative cosmetic outcome. The aim of our review was to identify the optimal timing of BR relating to radiotherapy delivery.
Using Cochrane Library, Embase, PubMed, Springer, Wanfang and CNKI, we performed a non-systematic review of articles published up to August 2021.
There is no hard evidence in favor of immediate, delayed or 2-stage BR when post-mastectomy radiation is indicated. Immediate and 2-stage BR seem to be valid alternatives to delayed BR.
Further research is essential in order to assess clinician and patient reported aesthetic outcomes and determine the optimal timing of BR in view of post-mastectomy radiotherapy, in breast cancer survivors.
接受乳房切除术的女性选择进行乳房重建（BR），以减轻身体形象困扰。辅助胸壁照射与不良的美容效果有关。我们的综述旨在确定与放射治疗相关的 BR 的最佳时机。
使用 Cochrane Library、Embase、PubMed、Springer、万方和中国知网，我们对截至 2021 年 8 月发表的文章进行了非系统性综述。
对于有指征进行乳房切除术后放疗的患者，没有证据支持立即、延迟或 2 期 BR。立即和 2 期 BR 似乎是延迟 BR 的有效替代方法。
为了评估乳腺癌幸存者乳房切除术后放射治疗的情况下，临床医生和患者报告的美学结果，并确定 BR 的最佳时机，需要进一步研究。
