ENT Department, Regional Hospital Gødstrup, Herning, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Acta Otolaryngol. 2022 Mar-Apr;142(3-4):229-233. doi: 10.1080/00016489.2022.2044518. Epub 2022 Mar 15.
Bilateral vestibulopathy (BVP) is a chronic and potentially very disabling condition. The impact of the vestibular loss on quality of life (QoL) is variable and still up for discussion. However, previous studies have reported that BVP has a negative impact of QoL.
AIMS/OBJECTIVES: The aim of the study was to evaluate the association between vestibulo-ocular reflex (VOR) gain and saccade pattern and patient reported QoL.
Ten patients fulfilling the Bárány criteria of BVP were included in the study. All patients underwent vestibular evaluation using Head Impulse Paradigm (HIMP) and Suppression Head Impulse Paradigm (SHIMP) and responded to Dizziness Handicap Inventory (DHI). DHI was used as a measurement for QoL.
Linear regression revealed a tendency to a correlation between lateral VOR-gain measured by HIMP or SHIMP and total DHI score. Covert saccades were related to low total DHI scores. No association was found between type of SHIMP saccade and QoL. No significant correlations were found.
A tendency was found towards a relationship between lateral VOR-gain by HIMP or SHIMP and total DHI score. The study also indicates that covert saccades are related to low impact on QoL.
双侧前庭病（BVP）是一种慢性且潜在的致残性疾病。前庭丧失对生活质量（QoL）的影响是可变的，仍在讨论中。然而，先前的研究报告称 BVP 对 QoL 有负面影响。
目的/目标：本研究旨在评估前庭眼反射（VOR）增益和扫视模式与患者报告的 QoL 之间的关联。
10 名符合 Bárány 双侧前庭病标准的患者纳入研究。所有患者均接受 Head Impulse Paradigm（HIMP）和 Suppression Head Impulse Paradigm（SHIMP）的前庭评估，并对 Dizziness Handicap Inventory（DHI）做出反应。DHI 用于测量 QoL。
线性回归显示，HIMP 或 SHIMP 测量的横向 VOR 增益与总 DHI 评分之间存在相关性的趋势。隐性扫视与总 DHI 得分较低有关。未发现 SHIMP 扫视类型与 QoL 之间存在关联。未发现显著相关性。
HIMP 或 SHIMP 的横向 VOR 增益与总 DHI 评分之间存在相关性的趋势。该研究还表明，隐性扫视与 QoL 影响较小有关。
