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肾移植后脑弓形虫病。病例报告。

Cerebral toxoplasmosis after renal transplantation. Case report.

作者信息

Tsanaclis A M, de Morais C F

出版信息

Pathol Res Pract. 1986 Jun;181(3):339-43. doi: 10.1016/S0344-0338(86)80113-3.

Abstract

A 19-year-old immunosuppressed male patient, after renal transplantation, developed at the 10th postoperative day (p.d.) fever, anemia hepatosplenomegaly and plaquetopenia; this condition deteriorated progressively and was complicated by drowsiness and generalized convulsions which persisted until the death at the 29th p.d. Autopsy revealed acute encephalitis characterized by multiple disseminated small lesions in the brain, containing cysts and trophozoites of Toxoplasma gondii. The diagnosis was not done during life, as occurred with most of previously reported cases, a fact that points to the necessity of preventive controlling measures of these patients before the institution of immunosuppressive measures.

摘要

一名19岁的免疫抑制男性患者,肾移植术后第10天出现发热、贫血、肝脾肿大和血小板减少;病情逐渐恶化,并出现嗜睡和全身性惊厥,持续至术后第29天死亡。尸检显示为急性脑炎,其特征是大脑中有多个散在的小病灶,含有刚地弓形虫的囊肿和滋养体。生前未做出诊断,正如大多数先前报道的病例一样,这一事实表明在采取免疫抑制措施之前对这些患者采取预防性控制措施的必要性。

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