Department of Dermatology, Venereology and Sexology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Dermatology, Department of Medicine, College of Medicine, Shaqra University, Dawadmi, Saudi Arabia.
J Cosmet Dermatol. 2022 Oct;21(10):4490-4502. doi: 10.1111/jocd.14918. Epub 2022 Apr 12.
Cyperus rotundus essential oil (CREO) is an anti-inflammatory and depigmenting agent that helps treat hyperpigmentation.
The purpose of this study was to evaluate the depigmenting effect of CREO on genital hyperpigmentation to that of arbutin (ARB), and to evaluate the association between genital lightening, genital self-image, sexual performance, and life quality.
Three hundred and eight healthy people were categorized into three groups: the CREO group, the ARB group, and the cold cream group (CC). In genital pigmentation, the tristimulus colorimeter is used to assess erythema and pigmentation. In addition, we aided in the development of the female genital self-image scale (FGSIS-4), the female sexual function index (FSFI), and the dermatology life quality index (DLQI).
The reduction in genital hyperpigmentation was significantly greater in the CREO and ARB groups than in the CC group; in physician global assessment and patients' self-assessment, the results in treated bikini with the CREO and ARB groups were excellent when compared with the CC. Furthermore, no adverse effects were found in the CREO group, but mild irritation was found in the ARB group; additionally, the percentage of hair growth, color and luminance reduction, and hair thickness were significantly reduced in the CREO group only. In addition, there were significantly different in FGSIS, FSFI, and DLQI between the CREO and ARB groups and the CC group.
CREO is equivalently efficacious in decreasing pigmentation, inflammation, and hair growth in the genital area. Positive changes boost female genital self-image, self-esteem, and sexual performance. Improving sexual health has a positive impact on quality of life.
香附精油(CREO)是一种具有抗炎和脱色作用的药物,可用于治疗色素沉着过度。
本研究旨在评估 CREO 对生殖器色素沉着过度的脱色效果,并评估生殖器变浅与生殖器自我形象、性表现和生活质量之间的关系。
将 308 名健康人分为 CREO 组、ARGB 组和冷霜组(CC)。采用三刺激比色计评估红斑和色素沉着。此外,我们协助开发了女性生殖器自我形象量表(FGSIS-4)、女性性功能指数(FSFI)和皮肤病生活质量指数(DLQI)。
与 CC 组相比,CREO 组和 ARGB 组的生殖器色素沉着减少更明显;在医生整体评估和患者自我评估中,与 CC 组相比,CREO 组和 ARGB 组治疗比基尼时的效果非常好。此外,在 CREO 组未发现不良反应,但在 ARGB 组发现轻度刺激;此外,仅在 CREO 组中,毛发的生长、颜色和亮度降低以及毛发厚度百分比显著降低。此外,FGSIS、FSFI 和 DLQI 在 CREO 组和 ARGB 组与 CC 组之间存在显著差异。
CREO 在减少生殖器区域的色素沉着、炎症和毛发生长方面同样有效。积极的变化可提高女性生殖器自我形象、自尊和性表现。改善性健康对生活质量有积极影响。